Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Osthole is a natural coumarin derivative predominantly found in Cnidium monnieri, a plant widely used in Traditional Chinese Medicine (TCM). Historically, extracts containing osthole have been used to support male reproductive health, particularly for issues such as impotence, infertility, and low libido. Ancient texts and TCM practitioners have described its use as a tonic to enhance sexual function and vitality.

While there is a substantial tradition of use, modern scientific evidence is limited. Some preclinical studies on animals suggest that osthole may influence testosterone production, improve sperm quality, or enhance erectile function, but these effects have not been robustly confirmed in human clinical trials. The mechanisms proposed include modulation of nitric oxide pathways and androgenic activity, but data remain preliminary. Therefore, while osthole is used in traditional settings for male reproductive support, scientific validation is still emerging, and the evidence base is not strong enough to grant a higher rating.

In summary, the use of osthole for male reproductive health is primarily justified by tradition, with some early scientific interest but insufficient clinical evidence at this time.

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