Evidence supporting the use of: Pygeum
For the body system: Male Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Pygeum (Prunus africana) is an herbal extract traditionally used in African medicine for urinary and prostate problems. Modern scientific research has focused on its effects in supporting male reproductive system health, particularly in the context of benign prostatic hyperplasia (BPH), a non-cancerous enlargement of the prostate gland common in older men. Several randomized, placebo-controlled clinical trials and meta-analyses have evaluated pygeum's efficacy. Results suggest that pygeum extract may modestly improve urinary symptoms associated with BPH, such as nocturia (nighttime urination), flow rate, and residual urine volume. A notable meta-analysis published in the journal British Journal of Urology (1995) concluded that pygeum was more effective than placebo in improving overall symptoms, though the quality of studies and reporting was variable.

The proposed mechanisms include anti-inflammatory activity, inhibition of prostatic growth factors, and modulation of hormones involved in prostate function. However, while there is a moderate level of scientific evidence supporting pygeum's benefit for lower urinary tract symptoms due to BPH, robust data on its direct effect on broader aspects of male reproductive health (e.g., fertility, testosterone levels) are lacking. Most studies are also short-term and use varying extract formulations, making comparisons difficult. In summary, pygeum has some scientific support for alleviating urinary symptoms linked to BPH, justifying its use in supporting aspects of the male reproductive system, but evidence is not conclusive or comprehensive across all areas of male reproductive health.

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