Evidence supporting the use of: Saffron
For the body system: Male Reproductive System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Saffron (Crocus sativus) has a long-standing role in traditional medicine, particularly in the Middle East and South Asia, where it has been used as an aphrodisiac and for improving male fertility. In recent years, scientific research has begun to validate some of these traditional claims. Several clinical studies have explored saffron's effect on male reproductive health, particularly in relation to erectile dysfunction (ED), semen quality, and libido.

A notable randomized, double-blind, placebo-controlled trial published in Phytomedicine (2009) found that saffron supplementation (60 mg/day for 12 weeks) led to significant improvements in sperm morphology and motility in infertile men, though it did not significantly alter sperm count. Additionally, other studies have indicated that saffron may improve erectile function and sexual satisfaction in men with ED, possibly due to its antioxidant properties and effects on nitric oxide pathways.

However, while these studies are promising, most have been small and of short duration. Systematic reviews and meta-analyses generally conclude that saffron shows potential for supporting aspects of male reproductive health, but larger, longer-term studies are needed for definitive recommendations. In summary, saffron's use for male reproductive health is supported by both tradition and emerging scientific evidence, though the quality and quantity of evidence is moderate.

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