Vitamin E, including its beta-tocopherol form, has been studied for its potential role in supporting the male reproductive system, primarily due to its antioxidant properties. Scientific research indicates that oxidative stress can negatively impact sperm quality and function, and antioxidants like vitamin E may help mitigate this damage. Several animal studies and some human clinical trials suggest that vitamin E supplementation can improve sperm motility, count, and overall semen quality in men with infertility issues. For example, a few randomized controlled trials have shown that vitamin E, sometimes in combination with other antioxidants, may improve certain parameters of male fertility, particularly in men with idiopathic infertility or high oxidative stress markers.

However, these effects are generally modest, and not all studies have found significant benefits. Much of the available research uses mixed tocopherols (not only beta-tocopherol but also alpha-tocopherol, the most biologically active form). The evidence is thus rated moderate to low, as systematic reviews and meta-analyses highlight the need for larger, better-designed trials to confirm efficacy. While vitamin E is traditionally considered important for reproductive health, especially due to early animal studies showing infertility in vitamin E-deficient rats, direct evidence for significant benefits in human male fertility is limited. Overall, there is some scientific basis for vitamin E’s use in supporting the male reproductive system, but the strength of the evidence is not robust.