Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E is an antioxidant that has been studied for its potential role in supporting male reproductive health, particularly in relation to sperm quality and fertility. The scientific evidence comes primarily from animal studies and a limited number of human clinical trials. Vitamin E's antioxidant properties help protect cell membranes, including those of sperm cells, from oxidative stress, which can impair sperm motility and function. Some studies have shown that vitamin E supplementation can improve certain semen parameters (such as motility and count) in infertile men, especially when combined with other antioxidants. For example, a few randomized controlled trials have reported modest improvements in sperm motility and a reduction in DNA damage in men with idiopathic infertility. However, the evidence is not robust or consistent enough to warrant a strong recommendation for its use in all men seeking to support reproductive health. Systematic reviews and meta-analyses generally find only small or inconsistent effects, and highlight the heterogeneity of study designs, doses, and populations studied. There is also insufficient evidence to suggest that vitamin E alone can significantly increase pregnancy rates. In summary, while some scientific rationale and limited clinical evidence exist for the use of vitamin E to support male reproductive health, the overall evidence base is weak to moderate and more high-quality studies are needed.

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