Evidence supporting the use of: Monolaurin
For the health condition: Mastitis
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Monolaurin, a monoglyceride derived from lauric acid (commonly found in coconut oil), is primarily known for its antimicrobial properties. Scientific interest in monolaurin as a supportive agent for mastitis arises from in vitro and some animal studies demonstrating its ability to disrupt lipid-coated bacteria, including Staphylococcus aureus—a major cause of infectious mastitis in breastfeeding women and dairy animals. Research has shown that monolaurin can inhibit the growth of certain Gram-positive bacteria, viruses, and fungi, and may reduce biofilm formation, which is relevant since biofilms can contribute to persistent infections in mastitis.
However, direct clinical evidence supporting the use of monolaurin for treating or preventing mastitis in humans is limited. Most of the available data come from laboratory studies or animal models, with only a few exploratory studies hinting at its potential benefit in reducing bacterial counts or inflammation associated with mastitis. There are no large-scale clinical trials confirming efficacy or safety in lactating women. Monolaurin is sometimes recommended in integrative or naturopathic circles based on its antimicrobial activity, but this is more extrapolative than evidence-based.
In summary, while there is a scientific rationale and some preclinical support for monolaurin’s use in mastitis (hence a rating of 2), robust clinical data are lacking. Its use should be considered experimental, and it should not replace standard medical treatment for mastitis.
Products containing monolaurin
Designs For Health
Liposomal Cat's Claw
Designs For Health
Monolaurin-Avail™