Relationship: Melanoma and vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Melanoma

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Source of validity: Scientific
Rating (out of 5): 2

Vitamin D has received scientific attention for its potential role in melanoma, a serious form of skin cancer. Epidemiological studies indicate that vitamin D deficiency may be associated with an increased risk of developing melanoma and with poorer outcomes in those already diagnosed. Laboratory studies have demonstrated that the active form of vitamin D (calcitriol) can inhibit the proliferation of melanoma cells and induce apoptosis (programmed cell death) in vitro. Additionally, vitamin D receptors are expressed on melanocytes (the cells from which melanomas originate), further supporting a possible biological link.

Despite these findings, clinical evidence supporting the use of vitamin D supplementation as a treatment for melanoma is limited. Most studies have focused on correlations between serum vitamin D levels and melanoma risk or prognosis, rather than on intervention trials assessing the impact of supplementation on survival or disease progression. As of now, there are no large, randomized controlled trials that demonstrate a clear benefit of vitamin D supplementation for the treatment of melanoma. Expert guidelines do recommend monitoring and correcting vitamin D deficiency in patients with melanoma, but this is primarily to support general bone and immune health rather than as a direct anti-cancer therapy.

In summary, while there is a scientific rationale and some preliminary evidence suggesting a potential role for vitamin D in melanoma support, the current level of direct clinical evidence is modest, and further research is needed before vitamin D can be considered a validated treatment for melanoma.

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Evidence supporting the use of: Vitamin D
For the health condition: Melanoma

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Synopsis

Other ingredients used for Melanoma

Other health conditions supported by vitamin D

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Health Concerns

Brands

Evidence supporting the use of: Vitamin DFor the health condition: Melanoma

Table of Contents

Synopsis

Other ingredients used for Melanoma

Other health conditions supported by vitamin D

Products containing vitamin D

Evidence supporting the use of: Vitamin D
For the health condition: Melanoma