Relationship: Memory and Brain Function and EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Eicosapentaenoic acid (EPA) is an omega-3 polyunsaturated fatty acid primarily found in fish oil. While EPA is most well-known for its cardiovascular and anti-inflammatory benefits, it has also been investigated for potential effects on memory and brain function. Several observational studies suggest omega-3 fatty acids, including both EPA and DHA (docosahexaenoic acid), are associated with better cognitive performance and a reduced risk of cognitive decline. However, the majority of scientific evidence for omega-3s and brain health focuses on DHA rather than EPA, as DHA is a major structural component of brain tissue.

Some randomized controlled trials (RCTs) have examined EPA supplementation in relation to mood disorders, such as depression, and found modest benefits. Fewer studies, however, have isolated EPA’s impact on memory or cognitive performance specifically. A few small RCTs and meta-analyses suggest that EPA, especially when combined with DHA, may offer mild cognitive benefits in older adults or those with mild cognitive impairment, but results are inconsistent, and effect sizes are generally small.

In summary, there is some scientific evidence supporting EPA’s use for brain health, but its direct effect on memory and cognition is less established than that of DHA. The evidence is rated as 2 out of 5: suggestive but not definitive, with further research needed to clarify EPA’s role and efficacy for memory and brain function.

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Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the health condition: Memory and Brain Function

Table of Contents

Synopsis

Other ingredients used for Memory and Brain Function

Other health conditions supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Health Concerns

Brands

Evidence supporting the use of: EPA (eicosapentaenoic acid)For the health condition: Memory and Brain Function

Table of Contents

Synopsis

Other ingredients used for Memory and Brain Function

Other health conditions supported by EPA (eicosapentaenoic acid)

Products containing EPA (eicosapentaenoic acid)

Evidence supporting the use of: EPA (eicosapentaenoic acid)
For the health condition: Memory and Brain Function