Evidence supporting the use of: Lemon balm
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lemon balm (Melissa officinalis) has a history of traditional use for improving mood and cognitive function, but there is also some scientific investigation into its effects on memory and brain function. Several small-scale clinical studies have evaluated the acute effects of lemon balm extracts on cognitive performance and mood in healthy adults. For example, a randomized, placebo-controlled, double-blind study published in 2002 found that single doses of lemon balm extract (300, 600, and 900 mg) led to improvements in calmness and memory performance in young adults. Other studies have investigated the use of lemon balm in combination with other herbs for cognitive function, with mixed results. The proposed mechanisms include inhibition of acetylcholinesterase (leading to increased acetylcholine levels in the brain) and antioxidant effects. However, most studies have been short-term, used small sample sizes, and focused on acute rather than long-term effects. The evidence for its use in populations with diagnosed cognitive impairment (such as Alzheimer’s disease) is limited and preliminary. While there is some scientific evidence suggesting that lemon balm may have modest cognitive-enhancing effects, especially in the short term, the overall quality and quantity of evidence is low. Larger, longer-term studies are needed to determine its effectiveness and safety for supporting memory and brain function.

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Products containing lemon balm

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