Evidence supporting the use of: Lipoic Acid
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lipoic Acid (also known as alpha-lipoic acid, or ALA) is an antioxidant compound that has been studied for its potential effects on memory and brain function, particularly in the context of neurodegenerative diseases like Alzheimer's. Some preclinical studies in animals have shown that ALA can reduce oxidative stress and may protect neurons from damage. In human studies, the evidence is limited but suggestive; a few small clinical trials have investigated ALA as an adjunct treatment for Alzheimer's disease and mild cognitive impairment. For example, one open-label pilot study reported that patients with Alzheimer's who received ALA supplementation experienced a slower rate of cognitive decline compared to expected rates, but this study and others like it have been small and not rigorously controlled. There is a theoretical rationale for its use, given its antioxidant properties and effects on mitochondrial function, but robust clinical data are lacking. Systematic reviews and meta-analyses generally conclude that while ALA is promising in preclinical models, there is insufficient high-quality evidence to recommend its use for memory or brain function in humans at this time. Therefore, the scientific evidence supporting lipoic acid for this indication is weak to modest, and more large, well-designed trials are needed.

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Other ingredients used for Memory and Brain Function

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fruit and vegetable blend (proprietary)
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Products containing Lipoic Acid

We currently have no products on Vitabase that contain this ingredient.