Evidence supporting the use of: Marine lipid
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Marine lipids, particularly omega-3 polyunsaturated fatty acids (PUFAs) such as eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), have been extensively studied for their effects on memory and brain function. DHA is a major structural component of neuronal cell membranes and is crucial for brain development and maintenance. Epidemiological studies have shown that populations with higher dietary intake of marine-derived omega-3s tend to have lower rates of cognitive decline and neurodegenerative diseases. Some randomized controlled trials (RCTs) have demonstrated that supplementation with marine lipids can improve certain aspects of cognitive function, especially in older adults with mild cognitive impairment or low baseline omega-3 status. For example, a 2012 meta-analysis published in "The Journal of Alzheimer's Disease" found modest benefits of omega-3 supplementation on memory in older adults. However, results across RCTs are mixed, with some studies showing no significant effect, particularly in healthy individuals or those with advanced cognitive decline. The mechanisms proposed include anti-inflammatory effects, improved neuronal membrane fluidity, and modulation of neurotransmitter pathways. While more research is needed to clarify the populations most likely to benefit, the scientific evidence does support a role for marine lipids in supporting memory and brain health, though the magnitude of effect is generally modest.

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Other ingredients used for Memory and Brain Function

2'-Fucosyllactose
Acai berry
Acetyl L-carnitine
algal oil
alpha-pinene
amino acids
anchovies
anthocyanins
ashwagandha
asparagus
astaxanthin
Waterhyssop
beet
berry flavor
beta caryophyllene
Bifidobacterium longum
bilberry
black currant
black garlic
sesame
black tea
blackberry
blueberry
Indian frankincense
broccoli
caprylic acid
catechins
caterpillar mushroom
chaga mushroom
Chinese salvia root
choline
cinnamon
citicoline
coenzyme Q10 (CoQ10)
coffee fruit
cordyceps
creatine monohydrate
turmeric
curcumin
d-alpha tocopherol
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
DPA (docosapentaenoic acid)
eleuthero
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
fish protein
folate
fruit and vegetable blend (proprietary)
fruit blend (proprietary)
ginkgo biloba
glycerophosphocholine (GPC)
gooseberry
gotu kola
grape
green tea
guarana
guayusa
hesperetin
huperzine A
inositol
jujube
kale
krill oil
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
l-carnitine
L-carnosine
L-serine
L-taurine
L-theanine
l-tyrosine
Lactobacillus reuteri
lecithin
lion's mane
lutein
luteolin
maca
mackerel
Marine lipid
Matcha
medium chain triglycerides (MCT)
Moringa
Muira puama
Acetyl-L-Tyrosine
Naringin
Niacin (vitamin B3)
Niacinamide (vitamin B3)
nicotinamide riboside
oat
oleic acid
olive
omega-3 fatty acids
ophiopogon root
perilla
phosphatidylcholine
phosphatidylserine
phospholipids
phytocannabinoids
pine bark
pollen
polygala root
pomegranate
pregnenolone
prolyl endopeptidase (PEP)
pumpkin
pyrroloquinoline disodium salt
quail egg
quercetin
reishi mushroom
resveratrol
Rhodiola
rutin
saffron
SAMe (S-adenosyl-L-methionine disulfate p-toluensulfate)
sardines
selenium
black ginger
specialized pro-resolving mediators (SPMs)
spinach
spirulina
strawberry
sulforaphane glucosinolate
Threonic acid
tocotrienols
tomato
Trans-pterostilbene
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ubiquinol
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vegetable and fruit blend (proprietary)
velvet bean
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vitamin B12
vitamin B6
vitamin C
vitamin D
vitamin D3
vitamin E
seaweed
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suma
jiaogulan
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lingzhi
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root tuber
ferulic acid
chrysanthemum
cistanche
lotus seed
royal jelly
terpene lactones
purslane
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biota seed
goji berry
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cocoa
AMP-activated protein kinase (AMPK)
ashitaba
1,3,7-Trimethylpurine-2,6-dione
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
5-methyltetrahydrofolate glucosamine
7,8-Dihydroxyflavone
arachidonic acid
apigenin
Aronia melanocarpa
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Alpha glyceryl
andrographolide
avocado
Agmatine
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amentoflavone
Agarwood
Acacetin
alpha-lipoic acid
anthocyanidins
ampelopsin
Acer truncatum
aniracetam
anthocyanosides
black seed
bilobalide
butylphthalide
beta-hydroxybutyrate
breadnut
Blepharis
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baccosides
Bacopin
baicalein
Basidiomycota
Boswellia
brahmi
Bacopa
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Bifidobacteria
bacoside
baicalin
bird\'s nest
centrophenoxine
Camellia sinensis
Centella triterpenes
Chinese mountain ant
cyanobacteria
Carnosine
catalpol
chebulic acid
cod liver oil
Codonopsis
cyanidin
cruciferous
Centella asiatica
cinnamic acid
chocolate
Chinese Ligustrum berry
creatine
catuaba
Convolvulus prostratus
crocetin
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Celastrus
cytidine
cola nut
Canscora
currant
carnosic acid
docosahexaenoic Acid
danshen
Dendrobium
decursin
decursinol
dibenzo-alpha pyrones
date
epicatechin
egg
ergothioneine
elk antler
emblicanin
eicosapentaenoic acid
Eucommia ulmoides
enokitake
folic acid
fucosterol
fo-ti
fish
flavanones
flavoglycosides
flavans
frankincense
flavanols
Flammulina velutipes
flavones
gallic acid
Ginsenosides
garcinol
ginkgetin
galantamine
Gypenoside
glucose
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ginkgolides
Glycosphingolipids
galangin
ginkgo flavone glycoside
Ginkgoside
Guaranine
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ginkgoheteroside
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gastrodin
Honokiol
Hericenones
hazelnut
hydroxytyrosol
hericium mushroom
Homotaurine
isoliquiritigenin
Idebenone
isovitexin
icariin
Jatamansi
Kaempferol
Lycium
lemon balm
longan
lysophosphatidylcholine
linalool
Methylcobalamin
mangiferin
Myricetin
Monounsaturated fat
Methylxanthine
Marine fat
Mate
Methoxylated flavones
magnolol
NADH
Naringenin
Nardostachys
Nobiletin
Nervonic acid
oolong tea
Osthole
Phosphocreatine
Puerain
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Piperine
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paraxanthine
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polyunsaturated fat
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punicalagins
paeoniflorin
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rosmarinic acid
Rehmannia
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Soy
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Shellfish
Salmon Oil
Salidroside
Sialic acid
Shankhpushpi
Salvianolic acid
Schisandrins
Schizandrol A
Shilajit
Safranal
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Taurine
Turmerones
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Uncaria
Uridine
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Vitexin
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Wogonin
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Xanthone
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Yumberry
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