Evidence supporting the use of: Osthole
For the health condition: Memory and Brain Function

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Osthole is a natural coumarin derivative found in several medicinal plants, most notably Cnidium monnieri (She Chuang Zi) and Angelica pubescens. In traditional Chinese medicine (TCM), these plants have been used for various purposes, including as tonics and for treating reproductive and skin conditions. There is some historical and anecdotal use of osthole-containing herbs for promoting vitality and, less commonly, for supporting cognitive health or "calming the spirit." However, the use of osthole specifically for memory and brain function is not a prominent feature in major historical texts, and its reputation in this area is less established than that of other traditional nootropics like Ginkgo biloba or Panax ginseng. Some modern preclinical studies (in vitro and in animal models) have explored osthole's potential neuroprotective and anti-inflammatory effects. A handful of these studies suggest that osthole may help reduce neuronal damage, improve learning and memory in rodents, and modulate neurotransmitter systems. However, these findings are preliminary, lack human clinical validation, and often use isolated osthole at concentrations unlikely to be achieved with typical herbal preparations. In summary, while there is some traditional use of osthole-containing herbs for general well-being and occasional references to cognitive support, robust evidence—especially from human studies—is lacking. The justification for osthole's use in supporting memory and brain function is therefore primarily traditional and based on limited preclinical research.

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Products containing Osthole

We currently have no products on Vitabase that contain this ingredient.