Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Vitamin E has been investigated for its potential role in supporting memory and brain function, particularly due to its antioxidant properties. Oxidative stress is believed to contribute to neurodegenerative diseases, including Alzheimer's disease. Several observational studies have noted that individuals with higher vitamin E intake or blood levels may have a lower risk of cognitive decline. However, randomized controlled trials (RCTs) have produced mixed results.

One landmark study (Sano et al., 1997) suggested that high-dose vitamin E supplementation slowed the progression of Alzheimer's disease in patients with moderate disease. However, more recent large-scale studies and systematic reviews have found little to no benefit of vitamin E supplementation in preventing cognitive decline in healthy older adults or in those with mild cognitive impairment. Some trials also raise concerns about potential risks, such as increased mortality with high-dose vitamin E.

Overall, while there is a plausible biological rationale and some early evidence supporting vitamin E’s role in brain health, the current scientific consensus is that supplementation does not provide consistent, meaningful cognitive benefits for most people. Thus, the evidence supporting vitamin E for memory and brain function is limited and not robust.

More about vitamin E
More about Memory and Brain Function

Other ingredients used for Memory and Brain Function

Other health conditions supported by vitamin E

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