Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Bupleurum falcatum is an herb with a long history of use in traditional Chinese medicine (TCM), primarily as part of multi-herb formulas such as Xiao Yao San (Free and Easy Wanderer). In TCM, it is used to harmonize the liver and support overall balance, including symptoms associated with menopause such as mood swings, irritability, and hot flashes. However, its use for menopause is based almost entirely on traditional practice rather than direct scientific study. There is a lack of robust clinical evidence specifically evaluating Bupleurum falcatum for menopausal symptoms. Most available research has focused on its anti-inflammatory, hepatoprotective, and immunomodulatory effects, rather than on hormonal or menopausal outcomes. The rationale for including Bupleurum falcatum in menopause-supporting formulas is rooted in the TCM approach, which addresses imbalances believed to underlie menopausal complaints. While some animal studies suggest potential neuroprotective and mood-regulating properties, these have not been adequately tested in clinical trials involving menopausal women. Therefore, while traditional use supports its inclusion for menopause-related symptoms, direct scientific validation remains minimal, and the overall level of evidence should be considered low.

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Douglas Laboratories AdrenoMend™