Evidence supporting the use of: Daidzein
For the health condition: Menopause

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Daidzein is an isoflavone, a type of phytoestrogen found primarily in soybeans and other legumes. Its use to support or treat menopause is grounded in scientific research, though the evidence is moderate rather than conclusive. Phytoestrogens like daidzein structurally resemble endogenous estrogens and can bind to estrogen receptors, exerting weak estrogenic or anti-estrogenic effects depending on the hormonal milieu. This has led to the hypothesis that daidzein may help alleviate menopausal symptoms such as hot flashes, night sweats, and mood disturbances, which are partly due to declining estrogen levels. Multiple randomized controlled trials (RCTs) and meta-analyses have investigated the effects of soy isoflavones, including daidzein, on menopausal symptoms. Some studies report a modest reduction in the frequency and severity of vasomotor symptoms, particularly hot flashes, compared to placebo. However, results are variable, and some trials find little or no benefit. The variability may be due to differences in study populations, isoflavone doses, duration, and individual differences in gut microbiota (which can affect daidzein metabolism to the more active compound equol). Systematic reviews generally conclude that soy isoflavones, including daidzein, are safe and may provide mild to moderate relief of menopausal symptoms, but are less effective than conventional hormone therapy. Overall, there is scientific rationale and some clinical evidence for their use, but effects are modest and not universal.

More about daidzein
More about Menopause

Other ingredients used for Menopause

27-deoxyactein
7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Achyranthes
Agnuside
Agrimonia pilosa
Akebia
Alchemilla
Alfalfa
Aloe vera
amaranth
Anemarrhena
anemarrhena asphodeloides
antler
Ashoka
ashwagandha
asparagus
astragalus
atractylodes
atractylone
banyan
barrenwort
bee pollen
bioflavonoids
black cohosh
black currant
black root
black seed
bupleurum falcatum
burdock
calcium
chaste tree
Chinese silkvine
Clary sage
Cnidium
cohosh
cordyceps
Crinum latifolium
Cynomorium
daidzein
damiana
danshen
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
dog rose
dong quai
dong quai root
durian
eleuthero
elk antler
equol (proprietary)
estrogen
Euryale seed
evening primrose oil
evening primrose oil
fenugreek
Ficus religiosa
fish oil
flaxseed
fo-ti
genistein
genistin
Glycetein
goji berry
hibiscus
HMR lignan
hops
horny goat weed
Hypericum
Indian frankincense
isoflavones
jujube
knotweed
kudzu
Labisia pumila
Lady's Mantle
lemon balm
licorice root
lignans
linden
lingzhi
Loranthus
lotus
Lycium
maca
macaenes
macamides
Marine lipid
Meadow sage
Melatonin
Miroestrol
Montanoa tomentosa
Moringa
Motherwort
Nettle
okra
omega-3 fatty acids
Ophiopogon
ophiopogon root
Phytoestrogens
pollen
Polygonum
pomegranate
Prickly Pear Cactus
Puerain
Pulsatilla
red clover
Rehmannia
rehmannia glutinosa
reishi mushroom
rhubarb
rockweed
Rooibos
root tuber
Rosa laevigata
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
rue
saffron
sage
seaweed
smilax
Soy
soy isoflavones
Soy Protein
soybean
Stone Root
Valerian root
Vervain
Viburnum
vitamin B6
vitamin D
vitamin D3
vitamin E
Vitex Agnus-Castus
Wild yam
Withanolides
Yellow-Fruit Nightshade

Products containing daidzein

We currently have no products on Vitabase that contain this ingredient.