Evidence supporting the use of: Evening primrose oil
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Evening primrose oil (EPO) is traditionally used to support women experiencing menopause, particularly for symptoms like hot flashes, night sweats, and mood swings. The use of EPO for menopausal symptoms arises from folk medicine and longstanding herbal practices, particularly in North America and Europe. The oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid thought to influence inflammation and hormone synthesis, which is the theoretical basis for its use in menopause management.

However, scientific evidence supporting EPO’s effectiveness for menopausal symptoms is limited and mixed. A small number of clinical trials have examined EPO’s effect on hot flashes, showing inconsistent results; some report modest improvements, while others find no significant benefit over placebo. Reviews and meta-analyses generally conclude that EPO is no more effective than placebo for most menopausal symptoms. The North American Menopause Society and other reputable organizations do not recommend EPO as a first-line or proven therapy.

In summary, while EPO is widely used in traditional and alternative medicine for menopause, scientific validation is lacking, and its efficacy has not been reliably demonstrated in rigorous studies. Its continued use is primarily rooted in tradition rather than strong scientific backing.

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Other ingredients used for Menopause

27-deoxyactein
7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Achyranthes
Agnuside
Agrimonia pilosa
Akebia
Alchemilla
Alfalfa
Aloe vera
amaranth
Anemarrhena
anemarrhena asphodeloides
antler
Ashoka
ashwagandha
asparagus
astragalus
atractylodes
atractylone
banyan
barrenwort
bee pollen
bioflavonoids
black cohosh
black currant
black root
black seed
bupleurum falcatum
burdock
calcium
chaste tree
Chinese silkvine
Clary sage
Cnidium
cohosh
cordyceps
Crinum latifolium
Cynomorium
daidzein
damiana
danshen
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
dog rose
dong quai
dong quai root
durian
eleuthero
elk antler
equol (proprietary)
estrogen
Euryale seed
evening primrose oil
evening primrose oil
fenugreek
Ficus religiosa
fish oil
flaxseed
fo-ti
genistein
genistin
Glycetein
goji berry
hibiscus
HMR lignan
hops
horny goat weed
Hypericum
Indian frankincense
isoflavones
jujube
knotweed
kudzu
Labisia pumila
Lady's Mantle
lemon balm
licorice root
lignans
linden
lingzhi
Loranthus
lotus
Lycium
maca
macaenes
macamides
Marine lipid
Meadow sage
Melatonin
Miroestrol
Montanoa tomentosa
Moringa
Motherwort
Nettle
okra
omega-3 fatty acids
Ophiopogon
ophiopogon root
Phytoestrogens
pollen
Polygonum
pomegranate
Prickly Pear Cactus
Puerain
Pulsatilla
red clover
Rehmannia
rehmannia glutinosa
reishi mushroom
rhubarb
rockweed
Rooibos
root tuber
Rosa laevigata
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
rue
saffron
sage
seaweed
smilax
Soy
soy isoflavones
Soy Protein
soybean
Stone Root
Valerian root
Vervain
Viburnum
vitamin B6
vitamin D
vitamin D3
vitamin E
Vitex Agnus-Castus
Wild yam
Withanolides
Yellow-Fruit Nightshade