Evidence supporting the use of: Ginsenoside
For the health condition: Menopause

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginsenosides, the primary active compounds in ginseng (Panax ginseng), have been studied for their potential benefits in managing menopausal symptoms. Scientific interest arises from their phytoestrogenic properties—meaning they can interact with estrogen receptors in the body. Several preclinical studies and a limited number of small-scale clinical trials have explored their effects on symptoms such as hot flashes, fatigue, and mood disturbances. Some studies suggest that ginsenosides may help modulate hormonal balance and exert mild estrogen-like effects, potentially alleviating certain menopausal complaints. For example, a few randomized controlled trials (RCTs) have reported improvements in well-being, mood, and sleep quality in postmenopausal women taking ginseng extracts, compared to placebo. However, results are inconsistent, with other studies showing no significant benefit.

The overall quality of evidence remains low to moderate, due to small sample sizes, short study durations, and variations in ginseng preparation and dosages. Systematic reviews generally conclude that while there is some promise, the evidence is insufficient to firmly recommend ginsenosides for menopause symptom management. Further, large, well-designed RCTs are necessary to confirm efficacy and safety. Therefore, use of ginsenosides for menopause is supported by a scientific rationale and preliminary evidence, but substantial gaps remain in the clinical data.

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Products containing Ginsenoside

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