Evidence supporting the use of: Hypericum (unspecified)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Hypericum, commonly known as St. John’s Wort, has a long history of use in traditional herbal medicine, most notably for its mood-modulating effects. Its application for menopause is largely grounded in traditional and empirical use rather than robust scientific validation. Many women experiencing menopause report symptoms such as mood swings, mild depression, anxiety, and sleep disturbances. Because Hypericum has been shown to have mild to moderate antidepressant effects in some clinical trials (primarily in non-menopausal populations), traditional practitioners sometimes recommend it for alleviating menopausal mood symptoms.

However, high-quality clinical trials specifically evaluating Hypericum for core menopausal symptoms—such as hot flashes, night sweats, or hormonal regulation—are limited. Some small studies and observational reports suggest it may modestly improve mood and quality of life in menopausal women, particularly when depression is present. Still, systematic reviews and meta-analyses generally conclude that the evidence base is insufficient and inconsistent for firm recommendations. Thus, its use for menopause is primarily justified by tradition and anecdotal experience rather than a well-established scientific rationale.

In summary, while Hypericum is traditionally used to support women during menopause, especially for mood-related symptoms, scientific validation specific to menopause is weak. Caution is advised due to potential drug interactions, particularly with antidepressants and hormonal therapies.

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