Evidence supporting the use of: Macaenes
For the health condition: Menopause
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Maca (Lepidium meyenii), sometimes referred to as "Macaenes" due to its content of macamides and macaenes (unique bioactive compounds), has a long history of traditional use in the Andes for promoting vitality and reproductive health, including symptoms associated with menopause. Indigenous populations in Peru have consumed Maca root to help manage hormonal balance, energy, and mood, particularly in women approaching or experiencing menopause.
Scientific studies investigating Maca's effect on menopausal symptoms are limited and generally small in scale. Some randomized controlled trials suggest that Maca supplementation may help reduce psychological symptoms (such as anxiety and depression) and improve sexual function in menopausal women. However, evidence regarding its effectiveness for classic vasomotor symptoms like hot flashes and night sweats is inconsistent. The mechanisms are not fully understood, but Maca does not appear to have estrogenic effects like some other herbal remedies. Instead, it may act through modulation of the hypothalamic-pituitary axis or by other bioactive compounds.
Overall, while there is a strong tradition of Maca use for menopause, scientific validation is modest, with most systematic reviews concluding that more rigorous, larger-scale studies are needed to confirm efficacy and safety.
Other ingredients used for Menopause
7-hydroxymatairesinol (HMR)Alfalfa
Aloe vera
ashwagandha
asparagus
astragalus
black cohosh
black currant
Indian frankincense
bupleurum falcatum
burdock
calcium
chaste tree
cordyceps
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dog rose
dong quai root
eleuthero
evening primrose oil
fenugreek
fish oil
flaxseed
genistein
genistin
hibiscus
HMR lignan
hops
knotweed
jujube
kudzu
licorice root
lignans
maca
marine lipid
melatonin
moringa
motherwort
nettle
okra
omega-3 fatty acids
ophiopogon root
pollen
pomegranate
rehmannia glutinosa
reishi mushroom
rose oil
saffron
sage
soybean
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
seaweed
wild yam
red clover
atractylodes
smilax
rubia cordifolia
bee pollen
lingzhi
root tuber
dioscorea
royal jelly
Equol (proprietary)
anemarrhena asphodeloides
barrenwort
goji berry
amaranth
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
Akebia
Antler
Achyranthes
Alchemilla
Agrimonia pilosa
Agnuside
Ashoka
Anemarrhena
Atractylone
Black Seed
Banyan
Bioflavonoids
Black root
Chinese Silkvine
Cohosh
Clary sage
Cnidium
Cynomorium
Crinum latifolium
DHEA
Danshen
Daidzein
Durian
Dong Quai
Euryale seed
Elk antler
Evening Primrose Oil
Estrogen
Fo-Ti
Ficus religiosa
Glycetein
Horny Goat Weed
Hypericum
Isoflavones
Lycium
lemon balm
Lady's Mantle
Linden
Lotus
Loranthus
Labisia pumila
Macamides
Montanoa tomentosa
Meadow sage
Miroestrol
Macaenes
Ophiopogon
Puerain
Pulsatilla
Prickly Pear Cactus
Phytoestrogens
Polygonum
Rue
Rubus
Rockweed
Rehmannia
Rose
Rooibos
Rosa laevigata
Rhubarb
Soy
Soy Protein
Stone Root
Vervain
Viburnum
Vitex Agnus-Castus
Withanolides
Yellow-Fruit Nightshade
Other health conditions supported by Macaenes
AmenorrheaAthletic and Exercise Aids
Energy (lack of)
Erectile Dysfunction
Fatigue
Infertility
Menopause
Menstrual Irregularity
PMS (general)
Sex Drive (low)
Stress
Testosterone (low)