Evidence supporting the use of: Melatonin
For the health condition: Menopause
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Melatonin, a hormone primarily known for regulating sleep-wake cycles, has been investigated for its potential role in supporting menopausal women, primarily due to its influence on sleep disturbances and circadian rhythm disruptions that often accompany menopause. Several small-scale clinical studies have explored melatonin’s effects on menopausal symptoms, especially insomnia, which is a common complaint during this period due to hormonal fluctuations. The evidence suggests that melatonin supplementation may help improve sleep quality and reduce the time it takes to fall asleep in peri- and postmenopausal women. Additionally, some research has posited that melatonin could have indirect benefits on mood regulation and may help modulate other menopausal symptoms, such as hot flashes, through its interaction with the endocrine system.
However, the scientific evidence is limited and not robust. The studies conducted have generally been small, short-term, and sometimes lack rigorous controls. Meta-analyses and systematic reviews have concluded that while melatonin shows promise for improving sleep in menopausal women, there is insufficient high-quality evidence to recommend it as a primary treatment for other menopausal symptoms. Major guidelines do not currently endorse melatonin as a standard therapy for menopause itself, but it may be considered for sleep disturbances when other interventions are unsuitable. In summary, there is moderate scientific rationale for melatonin's use in menopause—primarily for sleep support—but its overall evidence base remains weak.
Other ingredients used for Menopause
27-deoxyactein7-hydroxymatairesinol (HMR)
8-Prenylnaringenin
Achyranthes
Agnuside
Agrimonia pilosa
Akebia
Alchemilla
Alfalfa
Aloe vera
amaranth
Anemarrhena
anemarrhena asphodeloides
antler
Ashoka
ashwagandha
asparagus
astragalus
atractylodes
atractylone
banyan
barrenwort
bee pollen
bioflavonoids
black cohosh
black currant
black root
black seed
bupleurum falcatum
burdock
calcium
chaste tree
Chinese silkvine
Clary sage
Cnidium
cohosh
cordyceps
Crinum latifolium
Cynomorium
daidzein
damiana
danshen
DHEA
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dioscorea
dog rose
dong quai
dong quai root
durian
eleuthero
elk antler
equol (proprietary)
estrogen
Euryale seed
evening primrose oil
evening primrose oil
fenugreek
Ficus religiosa
fish oil
flaxseed
fo-ti
genistein
genistin
Glycetein
goji berry
hibiscus
HMR lignan
hops
horny goat weed
Hypericum
Indian frankincense
isoflavones
jujube
knotweed
kudzu
Labisia pumila
Lady's Mantle
lemon balm
licorice root
lignans
linden
lingzhi
Loranthus
lotus
Lycium
maca
macaenes
macamides
Marine lipid
Meadow sage
Melatonin
Miroestrol
Montanoa tomentosa
Moringa
Motherwort
Nettle
okra
omega-3 fatty acids
Ophiopogon
ophiopogon root
Phytoestrogens
pollen
Polygonum
pomegranate
Prickly Pear Cactus
Puerain
Pulsatilla
red clover
Rehmannia
rehmannia glutinosa
reishi mushroom
rhubarb
rockweed
Rooibos
root tuber
Rosa laevigata
rose
rose oil
royal jelly
Rubia cordifolia
Rubus
rue
saffron
sage
seaweed
smilax
Soy
soy isoflavones
Soy Protein
soybean
Stone Root
Valerian root
Vervain
Viburnum
vitamin B6
vitamin D
vitamin D3
vitamin E
Vitex Agnus-Castus
Wild yam
Withanolides
Yellow-Fruit Nightshade
Other health conditions supported by Melatonin
Addictions (general remedies for)Aging (prevention)
Alzheimer's Disease
Anxiety
Anxiety Disorders
Autism
Autoimmune Disorders
Cancer (natural therapy for)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Concussions
Dementia
Depression
Fatigue
Fibromyalgia Syndrome
Free Radical Damage
Glaucoma
Hypertension
Insomnia
Jet Lag
Menopause
Migraine
Multiple Sclerosis
Parkinson's Disease
Post Traumatic Stress Disorder
Seasonal Affective Disorder
Sleep (restless and disturbed)
Stress
Tinnitus
Ulcers
Products containing Melatonin
Vitabase
Healthy Sleep Support
Designs For Health
Insomnitol™ Capsules
Designs For Health
Insomnitol™ Chewables
Klean Athlete
Klean Melatonin
Pure Encapsulations
Liquid Melatonin
Thorne
Melaton-3 NSF
Thorne
Melaton-5
Designs For Health
Melatonin
Pure Encapsulations
Melatonin 0.5 mg
Pure Encapsulations
Melatonin 0.5 mg
Douglas Laboratories
Melatonin 1 mg
Douglas Laboratories
Melatonin 3 mg
Pure Encapsulations
Melatonin 20 mg
Pure Encapsulations
Melatonin 20 mg
Pure Encapsulations
Melatonin 3 mg
Pure Encapsulations
Melatonin 3 mg
Douglas Laboratories
Melatonin P.R.
Pure Encapsulations
Melatonin-SR
Designs For Health
Melatonin SRT™
Metagenics
MetaSleep®
Integrative Therapeutics
ProThrivers Wellness Sleep
