Evidence supporting the use of: Miroestrol
For the health condition: Menopause
Synopsis
Source of validity: Traditional
Rating (out of 5): 1
Miroestrol is a phytoestrogenic compound found primarily in the Thai herb Pueraria mirifica. Its use for menopause is rooted in traditional Thai medicine, where Pueraria mirifica has been used for centuries to alleviate symptoms associated with female aging, such as hot flashes and vaginal dryness. The rationale behind this use is that miroestrol and related compounds exert mild estrogenic effects, potentially compensating for declining estrogen levels during menopause.
However, scientific validation is limited. Some in vitro and animal studies suggest that miroestrol can bind to estrogen receptors and exert estrogen-like effects, but there is a paucity of robust human clinical trials. The few small-scale clinical studies available report subjective improvement in some menopausal symptoms with Pueraria mirifica supplementation, but these studies often suffer from methodological limitations such as small sample sizes and lack of rigorous controls. No definitive large-scale, placebo-controlled trials have established the efficacy or safety of miroestrol or Pueraria mirifica extracts for menopause management.
In summary, while traditional use and preliminary research provide some support for miroestrol in managing menopausal symptoms, scientific evidence remains weak and insufficient for formal medical endorsement.
Other ingredients used for Menopause
7-hydroxymatairesinol (HMR)alfalfa
aloe vera
ashwagandha
asparagus
astragalus
black cohosh
black currant
Indian frankincense
bupleurum falcatum
burdock
calcium
chaste tree
cordyceps
damiana
DHEA (dehydroepiandrosterone)
DIM (diindolylmethane)
dog rose
dong quai root
eleuthero
evening primrose oil
fenugreek
fish oil
flaxseed
genistein
genistin
hibiscus
HMR lignan
hops
knotweed
jujube
kudzu
licorice root
lignans
maca
marine lipid
melatonin
moringa
motherwort
nettle
okra
omega-3 fatty acids
ophiopogon root
pollen
pomegranate
rehmannia glutinosa
reishi mushroom
rose oil
saffron
sage
soybean
valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
seaweed
wild yam
red clover
atractylodes
smilax
rubia cordifolia
bee pollen
lingzhi
root tuber
dioscorea
royal jelly
Equol (proprietary)
anemarrhena asphodeloides
barrenwort
goji berry
amaranth
soy isoflavones
27-deoxyactein
8-Prenylnaringenin
akebia
Antler
Achyranthes
Alchemilla
Agrimonia pilosa
Agnuside
Ashoka
Anemarrhena
Atractylone
Black Seed
Banyan
Bioflavonoids
Black root
Chinese Silkvine
Cohosh
Clary sage
Cnidium
Cynomorium
Crinum latifolium
DHEA
Danshen
Daidzein
Durian
Dong Quai
Euryale seed
Elk antler
Evening Primrose Oil
Estrogen
Isoflavones
Lotus
Prickly Pear Cactus
Rose
Rhubarb
Soy Protein
Vervain
Other health conditions supported by Miroestrol
Breasts (enhance size)Menopause
PMS (general)
Sex Drive (low)