Evidence supporting the use of: Pimpinella (unspecified)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Pimpinella refers to a genus that includes several species, such as Pimpinella anisum (anise) and Pimpinella saxifraga. The use of Pimpinella, particularly Pimpinella anisum, in the context of menopause is primarily rooted in traditional medicine. Historical records show that anise has been used in various cultures for its purported estrogenic properties and to alleviate symptoms such as hot flashes, sleep disturbances, and mood swings associated with menopause. Traditional Persian and Middle Eastern medicine often recommended anise seeds or extracts for women experiencing menopausal complaints.

However, while there are a few small studies and animal experiments suggesting that Pimpinella anisum may have mild estrogen-like effects due to compounds such as anethole, the overall scientific evidence is limited and inconclusive. Most clinical trials are small, of short duration, or lack rigorous controls. There are no large-scale, high-quality randomized controlled trials that firmly establish the efficacy or safety of Pimpinella for menopause. Consequently, its use for supporting menopausal symptoms is justified by traditional rather than scientific evidence, and the overall quality of supporting data is low.

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