Siberian ginseng (Eleutherococcus senticosus), also known as eleuthero, has a long history of use in traditional medicine systems, particularly in Russia and East Asia. It is classified as an adaptogen, a substance thought to help the body resist various stressors. In the context of menopause, Siberian ginseng has been traditionally used to help alleviate symptoms such as fatigue, mood swings, and reduced vitality, which can be associated with menopausal transition. The rationale is based on its general tonic and adaptogenic properties rather than direct effects on hormonal balance or specific menopausal symptoms.

However, scientific evidence supporting the use of Siberian ginseng for menopause is minimal. Clinical trials specifically investigating its efficacy for menopausal symptoms are lacking. Most available studies focus on its potential to improve physical and mental performance, as well as its effects on the immune system, rather than on menopausal complaints. Reviews and authoritative sources, such as the National Center for Complementary and Integrative Health (NCCIH), note insufficient evidence for its use in menopause. Therefore, while traditional use exists, scientific validation for this specific indication is limited, resulting in a low evidence rating.