Evidence supporting the use of: Vitex (unspecified)
For the health condition: Menopause

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Vitex agnus-castus, commonly known as chaste tree or chasteberry, has a long history of traditional use for various female reproductive health concerns, including menopause. Traditional European herbal medicine has employed Vitex primarily for symptoms related to the menstrual cycle and premenstrual syndrome, but also for menopausal complaints such as hot flashes and mood disturbances. The rationale is based on observations that Vitex may influence the pituitary gland and thereby modulate hormonal balance, particularly by indirectly affecting levels of prolactin, luteinizing hormone, and possibly progesterone. However, the majority of rigorous scientific research has focused on premenstrual syndrome (PMS) and mastalgia rather than menopause itself. A limited number of small studies and anecdotal reports suggest possible benefit for menopausal symptoms, but these are generally of low methodological quality. Systematic reviews and meta-analyses point out insufficient evidence to recommend Vitex for menopausal symptoms due to a lack of robust clinical trials. In summary, the use of Vitex for menopause is primarily justified by traditional use rather than strong scientific validation, and current evidence from clinical studies is weak and inconclusive.

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