Evidence supporting the use of: Agrimonia pilosa
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Agrimonia pilosa, commonly known as hairy agrimony, has a long history of use in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Korean folk medicine. In these traditions, Agrimonia pilosa is often used to support gynecological health, including the treatment of menstrual irregularities such as excessive menstrual bleeding (menorrhagia), spotting, or irregular cycles. The herb is believed to possess astringent, hemostatic, and anti-inflammatory properties, which are thought to help regulate menstrual flow and reduce abnormal uterine bleeding. The traditional use is supported by various classical herbal texts and documented folk practices, where decoctions or extracts of the whole plant are administered for these purposes.

However, the scientific evidence for Agrimonia pilosa’s effectiveness in treating menstrual irregularity is limited. While some preclinical studies indicate that the plant contains bioactive compounds such as flavonoids and tannins, which may have hemostatic and anti-inflammatory effects, there are no well-designed human clinical trials specifically assessing its efficacy for menstrual disorders. Most of the available data come from in vitro or animal studies or are anecdotal reports in ethnobotanical literature. Thus, the use of Agrimonia pilosa for menstrual irregularity is primarily justified by traditional use, with only modest indirect pharmacological support from laboratory studies, resulting in a low to moderate evidence rating.

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