Evidence supporting the use of: Bupleurum (unspecified)
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bupleurum, primarily Bupleurum chinense and Bupleurum falcatum, is a classic herb in Traditional Chinese Medicine (TCM) and Japanese Kampo medicine. Its use for menstrual irregularity is documented in TCM, where it appears in formulas such as Xiao Yao San (Free and Easy Wanderer Powder). This formula is traditionally prescribed to "soothe the liver" and regulate menstruation, particularly when menstrual irregularity is believed to be rooted in "liver qi stagnation," a TCM diagnostic concept. Case reports, anecdotal evidence, and traditional texts support its use for symptoms such as irregular cycles, premenstrual syndrome, and dysmenorrhea. However, while some modern animal studies indicate potential hormonal or anti-inflammatory effects, there is a lack of rigorous clinical trials specifically evaluating Bupleurum for menstrual irregularity in humans. Thus, scientific support for this use is minimal, and its continued use is rooted in centuries of empirical observation and tradition rather than robust, modern scientific validation.

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