Lady's Mantle (Alchemilla vulgaris) has a long history of traditional use in European herbal medicine, particularly for women's health issues such as menstrual irregularity, heavy periods, and cramping. Historical records indicate that herbalists since the Middle Ages have recommended Lady's Mantle as a uterine tonic, purportedly to regulate menstrual cycles and alleviate excessive menstrual bleeding. The herb is typically prepared as a tea or tincture and was often included in remedies for "female complaints."

The rationale behind its use is attributed mainly to its astringent properties, derived from its high tannin content, which theoretically could help reduce excessive bleeding. Some traditional sources also suggest that Lady's Mantle may have mild hormonal or anti-inflammatory effects, though this is not well characterized.

Despite its widespread use in folk medicine, scientific evidence supporting the efficacy of Lady's Mantle for menstrual irregularity is limited. There are a few laboratory studies exploring its phytochemical constituents and general pharmacological properties, but there are no robust clinical trials or substantial scientific reviews confirming its effect on menstrual regulation. Thus, the current use of Lady's Mantle for menstrual irregularity is based primarily on tradition and anecdotal evidence rather than solid scientific validation.