Evidence supporting the use of: Licorice root
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM) and Ayurveda, for a variety of female reproductive concerns, including menstrual irregularity. In TCM, licorice is often included in herbal formulas to "harmonize" the ingredients and is sometimes prescribed for conditions associated with hormonal imbalance and irregular menstrual cycles. The traditional rationale is based on licorice's purported ability to tonify the body, reduce inflammation, and alleviate stress, which are seen as contributing factors to menstrual irregularities.

From a scientific perspective, licorice root contains phytoestrogens and compounds such as glycyrrhizin, which can influence the hormonal system. Some small clinical studies and animal research have suggested that licorice may modulate estrogen and androgen levels, potentially impacting menstrual cycles. For example, a few studies have explored licorice's use in managing polycystic ovary syndrome (PCOS), a common cause of menstrual irregularity, with mixed results. However, robust, high-quality clinical trials specifically evaluating licorice root for general menstrual irregularity are lacking.

Overall, while the traditional use of licorice root for menstrual irregularity is well-documented, scientific validation remains limited. The available evidence is preliminary and not strong enough to firmly support its use for this indication. Care must also be taken with licorice supplementation, as excessive consumption can lead to serious side effects, including hypertension and electrolyte imbalances.

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Other health conditions supported by licorice root

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