Evidence supporting the use of: Motherwort
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Motherwort (Leonurus cardiaca) has a long history of use in traditional herbal medicine for supporting menstrual health, particularly in cases of menstrual irregularity. Historically, motherwort has been employed by herbalists in Europe, Asia, and North America as an emmenagogue—an agent thought to stimulate menstrual flow and regulate cycles. Its use can be traced back to texts from ancient Greece and through to Medieval European herbal traditions where it was recommended for “female complaints.” The rationale behind its use is tied to its mild uterine stimulant effects, believed to promote regular menstruation and alleviate symptoms such as cramps and delayed periods.

However, scientific research on motherwort’s efficacy for menstrual irregularity is limited. The plant contains various phytochemicals, including leonurine and stachydrine, which may have mild uterotonic effects based on animal studies, but robust clinical trials in humans are lacking. Some small studies and anecdotal reports suggest potential benefit, but these are not sufficient to draw definitive conclusions about its effectiveness or safety for this purpose.

In summary, the use of motherwort for menstrual irregularity is primarily justified by traditional and historical use, with only modest scientific evidence available. As such, it is important for individuals to consult healthcare providers before using motherwort for menstrual concerns, especially in the context of potential contraindications or interactions.

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