Evidence supporting the use of: Prickly ash
For the health condition: Menstrual Irregularity
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Prickly ash (Zanthoxylum americanum or Zanthoxylum clava-herculis) has been used in North American traditional herbal medicine, particularly by Indigenous peoples and later by 19th-century Eclectic physicians, for various conditions, including menstrual irregularity. Historically, prickly ash bark was considered a stimulant and circulatory tonic, believed to "move the blood" and stimulate bodily functions. It was sometimes recommended for amenorrhea (absence of menstruation) or dysmenorrhea (painful menstruation), based on the concept that improving blood flow or stimulating the pelvic organs could help regulate or restore menstrual cycles. However, this use is based primarily on traditional and empirical knowledge rather than rigorous scientific evidence. Contemporary herbal texts sometimes mention the historical use of prickly ash for menstrual complaints, but there are no well-designed clinical trials or robust pharmacological studies confirming its efficacy or safety for this condition. The supposed mechanism—improving peripheral circulation—remains speculative and has not been directly linked to menstrual regulation in scientific literature. Overall, while prickly ash has a documented history of use for menstrual irregularity in traditional medicine systems, the evidence is largely anecdotal or based on the historical medical theories of the time, rather than validated by modern research. Consequently, its evidence rating for this use is low (2/5).
Other ingredients used for Menstrual Irregularity
ashwagandhablack cohosh
black pepper
calcium
cassia bark
chaste tree
dong quai root
evening primrose oil
fenugreek
Japanese sophora
licorice root
lovage
maca
motherwort
vitamin B6
vitamin C
vitamin D
wild yam
zinc
red clover
anise
blackboard tree
fumaria parviflora
rubia cordifolia
blessed thistle
lingusticum wallichii
yarrow
prickly ash
juniper berries
dioscorea
queen of the meadow
shepherd's purse
wood betony
akebia
Apple Cider Vinegar
Agastache
Angelica
Agrimony
Achyranthes
Abrus
Alchemilla
Aletris
Ajuga
Anserina
Aerva lanata
Agrimonia pilosa
Agnuside
Ashoka
Abuta
Betony
Blue Cohosh
Blue Flag
Blepharis
Balsam
Big Quaking Grass
Black Gram
Bethroot
Baccharoides anthelmintica
black salt
Black root
Bupleurum
Black Hellebore
Bergenia
Cumin
Cohosh
Clary sage
Calotropis gigantea
Cnidium
Clerodendrum phlomidis
Cactus
Cinquefoil
Cyathula
Corktree
Cowslip
Chirata
Calamus
Corydalis
Didymocarpus
Dong Quai
Erythropalum scandens
Erodium cicutarium
Euryale seed
Elephant's Head
Evening Primrose Oil
Estrogen
Fig
False Unicorn Root
Little ironweed
Pennyroyal
Rose
Spikenard
Snakeroot (unspecified)
Other health conditions supported by prickly ash
Abdominal PainAcid Indigestion
Appetite (deficient)
Backache
Bronchitis
Circulation (poor)
Cough (general)
Cough (spastic)
Diarrhea
Digestion (poor)
Dyspepsia
Edema
Gas and Bloating
Gastritis
Indigestion
Infection
Inflammation
Lymph Nodes or Glands (swollen)
Menstrual Irregularity
Nausea and Vomiting
Pain (general remedies for)
Rashes and Hives
Ulcers
Wounds and Sores