Evidence supporting the use of: Prickly ash
For the health condition: Menstrual Irregularity
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Prickly ash (Zanthoxylum americanum or Zanthoxylum clava-herculis) has been used in North American traditional herbal medicine, particularly by Indigenous peoples and later by 19th-century Eclectic physicians, for various conditions, including menstrual irregularity. Historically, prickly ash bark was considered a stimulant and circulatory tonic, believed to "move the blood" and stimulate bodily functions. It was sometimes recommended for amenorrhea (absence of menstruation) or dysmenorrhea (painful menstruation), based on the concept that improving blood flow or stimulating the pelvic organs could help regulate or restore menstrual cycles. However, this use is based primarily on traditional and empirical knowledge rather than rigorous scientific evidence. Contemporary herbal texts sometimes mention the historical use of prickly ash for menstrual complaints, but there are no well-designed clinical trials or robust pharmacological studies confirming its efficacy or safety for this condition. The supposed mechanism—improving peripheral circulation—remains speculative and has not been directly linked to menstrual regulation in scientific literature. Overall, while prickly ash has a documented history of use for menstrual irregularity in traditional medicine systems, the evidence is largely anecdotal or based on the historical medical theories of the time, rather than validated by modern research. Consequently, its evidence rating for this use is low (2/5).
Other ingredients used for Menstrual Irregularity
AbrusAbuta
Achyranthes
Aerva lanata
Agastache
Agnuside
Agrimonia pilosa
Agrimony
Ajuga
Akebia
Alchemilla
Aletris
Angelica
anise
Anserina
apple cider vinegar
Ashoka
ashwagandha
Baccharoides anthelmintica
balsam
Bergenia
bethroot
betony
big quaking grass
black cohosh
black gram
Black Hellebore
black pepper
black root
black salt
blackboard tree
Blepharis
blessed thistle
blue cohosh
blue flag
Bupleurum
cactus
calamus
calcium
Calotropis gigantea
cassia bark
chaste tree
chirata
cinquefoil
Clary sage
Clerodendrum phlomidis
Cnidium
cohosh
corktree
Corydalis
cowslip
cumin
Cyathula
Didymocarpus
dioscorea
dong quai
dong quai root
elephant\'s head
Erodium cicutarium
Erythropalum scandens
estrogen
Euryale seed
evening primrose oil
evening primrose oil
false unicorn root
fenugreek
fig
Fumaria parviflora
Japanese sophora
joe-pye
juniper berries
knotgrass
Labisia pumila
Lady's Mantle
lemon balm
Leptadenia
Lesser speargrass
licorice root
little ironweed
Lophira lanceolata
lovage
maca
macaenes
Marjoram
Mentha haplocalyx
Mezoneuron benthamianum
Montanoa tomentosa
Motherwort
Mung bean
Pennyroyal
Pentatropis capensis
Phytoestrogens
Plectranthus amboinicus
Potentilla
prickly ash
Pulsatilla
Qin Jiao
queen of the meadow
red clover
rose
Rubia cordifolia
Rubus
Sanguisorba
Semecarpus anacardium
Semiaquilegia
shepherd's purse
Snakeroot
Southernwood
Speedwell
Spikenard
Szechuan lovage
Tarragon
Tropical jewel hisbiscus
Turtle Head
Viburnum
vitamin B6
vitamin C
vitamin D
Vitex Agnus-Castus
Wild yam
Wood betony
Yarrow
Zinc
Other health conditions supported by prickly ash
Abdominal PainAcid Indigestion
Appetite (deficient)
Backache
Bronchitis
Circulation (poor)
Cough (general)
Cough (spastic)
Diarrhea
Digestion (poor)
Dyspepsia
Edema
Gas and Bloating
Gastritis
Indigestion
Infection
Inflammation
Lymph Nodes or Glands (swollen)
Menstrual Irregularity
Nausea and Vomiting
Pain (general remedies for)
Rashes and Hives
Ulcers
Wounds and Sores
