Evidence supporting the use of: Rubia cordifolia
For the health condition: Menstrual Irregularity

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Rubia cordifolia (commonly known as Manjistha) has a long-standing use in traditional Ayurvedic medicine, primarily for its blood-purifying and anti-inflammatory properties. In the context of menstrual irregularity, classical Ayurvedic texts describe Manjistha as a herb that helps regulate menstrual flow and alleviate gynecological disorders. Its rationale in traditional medicine is based on its believed ability to balance the doshas, especially by cooling excess "pitta" (fire) in the blood, which is thought to underlie many menstrual disturbances.

Scientific studies supporting Rubia cordifolia’s efficacy in menstrual irregularity are limited and largely preclinical. Some animal studies suggest that extracts of the plant may influence uterine muscle contraction or modulate hormone levels, but robust clinical trials in humans are lacking. The available literature typically cites its traditional use and general anti-inflammatory, antioxidant, and hemostatic effects that may theoretically benefit menstrual health. However, these effects have not been unequivocally demonstrated in modern clinical settings for the specific indication of menstrual irregularity.

In summary, while Rubia cordifolia is widely used in traditional medicine for menstrual problems, scientific validation remains insufficient. Its use for menstrual irregularity is primarily justified by tradition, with a moderate historical evidence base but low direct scientific support.

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