Evidence supporting the use of: Five-leaf Chastetree
For the health condition: Menstruation (scant)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Five-leaf Chastetree (Vitex negundo) is traditionally used in various systems of medicine, particularly in Ayurveda and Unani, to support menstrual health, including scanty menstruation (oligomenorrhea). Historical texts and ethnomedicinal records document the use of Vitex negundo leaves, seeds, and roots as emmenagogues—substances believed to stimulate or regulate menstrual flow. The plant is thought to exert effects on the female reproductive system, with traditional practitioners often prescribing it for menstrual irregularities, dysmenorrhea, and related complaints. The rationale is based on its purported ability to balance hormones and promote uterine health. However, the majority of available evidence supporting its use is anecdotal and based on traditional knowledge or case reports rather than modern clinical trials. While some preclinical studies suggest anti-inflammatory and analgesic properties, there is insufficient scientific research directly validating its benefit in treating scanty menstruation. Most scientific studies of the genus Vitex related to menstruation have focused on Vitex agnus-castus (chaste tree), not Vitex negundo. Therefore, the use of Five-leaf Chastetree for scant menstruation is mainly justified by tradition, and the quality of evidence is low, with a lack of robust clinical data to confirm efficacy or elucidate mechanisms of action.

More about Five-leaf Chastetree
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