Evidence supporting the use of: Rhodiola
For the health condition: Mental Illness

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rhodiola rosea is an adaptogenic herb traditionally used in Russia and Scandinavia to improve resilience to stress, fatigue, and mood disturbances. Over the past two decades, a growing body of scientific research has explored its potential for supporting mental health, particularly symptoms related to stress-induced fatigue, mild depression, and anxiety. Several randomized controlled trials (RCTs) and meta-analyses suggest that Rhodiola extracts may have modest benefits for reducing symptoms of mild-to-moderate depression and generalized anxiety, as well as improving cognitive function under stress. The mechanisms are thought to involve modulation of the hypothalamic-pituitary-adrenal (HPA) axis, enhancement of serotonin and dopamine activity, and reduction of oxidative stress.

However, the overall quality of the clinical evidence is limited by small sample sizes, short study durations, and heterogeneity in Rhodiola preparations and dosing. While results are promising for mild/subthreshold depression and anxiety, there is insufficient evidence to support Rhodiola as a primary treatment for major depressive disorder, severe anxiety disorders, or other serious mental illnesses. Most guidelines do not recommend it as a first-line therapy, but it may be considered as an adjunct or for individuals preferring herbal approaches for mild symptoms. Traditional use is strong, but scientific validation remains moderate at best, warranting a rating of 2 out of 5 for evidence supporting its use in mental illness.

More about rhodiola
More about Mental Illness