Evidence supporting the use of: Gluthathione
For the health condition: Mercury Poisoning
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Glutathione is a tripeptide molecule that functions as a major intracellular antioxidant and plays a key role in cellular detoxification processes. Its use in supporting or treating mercury poisoning is based on its biochemical ability to bind to heavy metals, including mercury, through its sulfhydryl (-SH) group, forming complexes that can be more readily excreted by the body. Scientific studies, primarily in vitro and in animal models, indicate that glutathione participates in the detoxification of mercury by facilitating its removal via the kidneys and bile. Depletion of glutathione levels has been observed to increase the toxicity of mercury compounds, while supplementation or enhancement of glutathione synthesis may reduce mercury-induced oxidative stress and cellular damage. However, direct clinical evidence in humans for the efficacy of glutathione supplementation in treating mercury poisoning is limited. Most standard medical protocols for mercury toxicity rely on chelating agents such as dimercaprol (BAL), DMSA, or DMPS, which have more robust clinical data. A few small studies and case reports suggest a supportive role for glutathione, especially as an adjunct to chelation therapy, but these are not sufficient to establish glutathione as a primary treatment. In summary, the use of glutathione in mercury poisoning is supported by mechanistic and some preclinical evidence but lacks strong, large-scale clinical validation.
Other health conditions supported by Gluthathione
Acquired Immune Deficiency SyndromeAlcoholism
Autoimmune Disorders
Cancer (prevention)
Cancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Chronic Obstructive Pulmonary Disorder
Cirrhosis of the Liver
Convalescence
Diabetes
Diabetic Retinopathy
Fatigue
Fatty Liver Disease
Free Radical Damage
Heavy Metal Poisoning
Hepatitis
Inflammation
Inflammatory Bowel Disorders
Liver Detoxification
Mercury Poisoning