Evidence supporting the use of: Anthocyanidins
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Anthocyanidins are a class of flavonoids found in various fruits and vegetables, notably in berries, red cabbage, and purple sweet potatoes. Their use in supporting or treating Metabolic Syndrome is primarily justified by emerging scientific evidence from both preclinical and clinical research. Several studies suggest that anthocyanidins possess antioxidant and anti-inflammatory properties that can positively influence components of Metabolic Syndrome, such as insulin resistance, dyslipidemia, hypertension, and obesity.
Animal studies have demonstrated that diets rich in anthocyanidins can improve glucose metabolism, reduce adiposity, and lower blood pressure. Human observational studies and some small-scale clinical trials have found associations between higher dietary intake of anthocyanin-rich foods and reduced risk factors for Metabolic Syndrome. For example, a 2016 meta-analysis of prospective cohort studies published in "Critical Reviews in Food Science and Nutrition" reported that greater anthocyanin consumption was linked to a lower risk of developing Metabolic Syndrome. Proposed mechanisms include improved endothelial function, modulation of lipid profiles, and reduction of systemic inflammation.
However, while the evidence is promising, it remains moderate (rated 3 out of 5) due to a relative lack of large-scale, well-controlled human intervention trials specifically targeting Metabolic Syndrome as an outcome. Thus, anthocyanidins are considered scientifically supported for this use, but further research is needed to clarify their efficacy and establish clear clinical recommendations.
Other ingredients used for Metabolic Syndrome
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anchovies
anthocyanins
asparagus
bacillus subtilis
banaba
barley
berberine
Beta-Glucan
beta-sitosterol
bifidobacterium longum
bitter melon
black garlic
blueberry
brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
matcha
medium chain triglycerides (MCT)
moringa
naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
trans-pterostilbene
Urolithin A
vanadium
vanadyl sulfate
vitamin C
vitamin D
wheat grass
whey protein
xylooligosaccharides
zinc
β-nicotinamide mononucleotide (NMN)
algae
kidney beans
AMP-activated protein kinase (AMPK)
1-deoxynojirimycin
15,16-Dihydrotanshinone I
12-methylcarnosic acid
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
Alpha Glucans
Ankaflavin
Apigenin
Aronia melanocarpa
Antrodia camphorata
Auricularia
Antirrhinin
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Alpha phytosterol
Algal protein
Arabinoxylan
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Bifidobacterium adolescentis
Beta-hydroxybutyrate
Blakeslea trispora
Bean
Betanin
Brazil nut
Charantin
California chia
Cardarine
Cyanobacteria
Capsinoids
Cyanidin
chlorogenic acid
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
Cynaropicrin
Cystoseira canariensis
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Dunaliella
Dihydrocapsiate
Dragon Fruit
Dihydrolipoic Acid
D-Pinitol
Diosgenin
Ergothioneine
Ecklonia
peanut
Pistachio
Other health conditions supported by anthocyanidins
Aging (prevention)Arteriosclerosis
Arthritis
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Diabetes
Diabetic Retinopathy
Eye Problems
Eyesight (poor)
Free Radical Damage
Gingivitis
Heart (weakness)
Hemorrhoids
Hypertension
Inflammation
Inflammatory Bowel Disorders
Macular Degeneration
Memory and Brain Function
Metabolic Syndrome
Rheumatoid Arthritis
Skin Care (general)
Ulcers
Varicose Veins
Wounds and Sores