Evidence supporting the use of: Beta-cyclodextrin
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Beta-cyclodextrin is a cyclic oligosaccharide primarily used as a pharmaceutical excipient to improve the solubility and bioavailability of drugs. However, there is emerging scientific interest in its potential metabolic effects. Some preclinical studies suggest that beta-cyclodextrin can bind cholesterol and reduce its absorption, leading to lower blood cholesterol levels in animal models. Additionally, a few small-scale studies have investigated its effects in the context of obesity, lipid metabolism, and metabolic syndrome. For example, animal research indicates that dietary beta-cyclodextrin supplementation can reduce serum cholesterol and improve some metabolic parameters in rodent models of metabolic syndrome. However, data from human trials are extremely limited, and the clinical relevance remains uncertain.
To date, there is no robust, large-scale clinical evidence supporting the routine use of beta-cyclodextrin for the treatment or prevention of metabolic syndrome in humans. Most of the current evidence stems from preclinical work or very preliminary human studies. As a result, while there is some scientific rationale and early-stage evidence, the overall strength and quality of the evidence is low, and beta-cyclodextrin cannot be considered a validated therapy for metabolic syndrome at this time.
Other ingredients used for Metabolic Syndrome
7-hydroxymatairesinol (HMR)7-Keto-DHEA
Acai berry
Akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anchovies
anthocyanins
asparagus
bacillus subtilis
banaba
barley
berberine
Beta-Glucan
beta-sitosterol
bifidobacterium longum
bitter melon
black garlic
blueberry
brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
matcha
medium chain triglycerides (MCT)
moringa
naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
trans-pterostilbene
Urolithin A
vanadium
vanadyl sulfate
vitamin C
vitamin D
wheat grass
whey protein
xylooligosaccharides
zinc
β-nicotinamide mononucleotide (NMN)
Algae
kidney beans
AMP-activated protein kinase (AMPK)
1-deoxynojirimycin
15,16-Dihydrotanshinone I
12-methylcarnosic acid
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
Alpha Glucans
Ankaflavin
Apigenin
Aronia melanocarpa
Antrodia camphorata
Auricularia
Antirrhinin
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Alpha phytosterol
Algal protein
Arabinoxylan
Alpha methyl Tetradecylthioacetic Acid
Arjunolic acid
Bifidobacterium adolescentis
Beta-hydroxybutyrate
Blakeslea trispora
Bean
Betanin
Brazil nut
Charantin
California chia
Cardarine
Cyanobacteria
Capsinoids
Cyanidin
chlorogenic acid
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
Cynaropicrin
Cystoseira canariensis
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Dunaliella
Dihydrocapsiate
Dragon Fruit
Dihydrolipoic Acid
D-Pinitol
Diosgenin
Ergothioneine
Evodiamine
Ecklonia
Fucosterol
Foxtail millet
Fucoxanthin
Flavanols
Fructan
Ginsenosides
Glucan peptides
Galactooligosaccharides
Guanidinopropionic Acid (GPA )
Guggulsterones
Glucoraphanin
Garbanzo bean
Glucosinolates
Hydroxytyrosol
Isomaltulose
Isoalantolactone
Irvingia gabonensis
Konjac
Kamut
Lipstatin
Legume protein
Lentil
Lupin
Monacolin
Maslinic Acid
Mangiferin
Mulberroside A
Monounsaturated Fat
Momordicosides
Naringenin
Neoeriocitrin
Nobiletin
Oolong Tea
Oligosaccharides
Oleoylethanolamide
Phycocyanin
Pyrroloquinoline Quinone
Phlorizin
Phaeophyceae
Phytoplankton
Polychitosamine
Polysaccharides
Pinitol
Polydatin
punicalin
Polyunsaturated Fat
Pleurotus eryngii
Pu-Er Tea
Punicalagins
Palatinose
Punicic acid
peanut
Pistachio
Rebaudioside
Red miso
Schizochytrium Oil
Schizochytrium
Salmon Oil
Salidroside
Syringic acid
Salacia
Sesamolin
Sesamin
Sinensetin
Sulforaphane
Tagatose
Tetradecylthioacetic acid
Thylakoid
Tyrosol
Tangeretin
Tanshinone
Theaflavin
Theabrownin
Xanthohumol
Yacon
Other health conditions supported by beta-cyclodextrin
Cancer Treatment (reducing side effects)Cholesterol (high)
Metabolic Syndrome