Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Campesterol is a phytosterol—a plant-derived compound structurally similar to cholesterol—that is found in various vegetables, fruits, nuts, and seeds. Its primary mechanism of action is the inhibition of intestinal absorption of dietary cholesterol, which leads to decreased plasma cholesterol levels. Because dyslipidemia (abnormal lipid profiles) is a central feature of Metabolic Syndrome, and elevated LDL cholesterol is a key risk factor, interventions that improve lipid profiles are of interest in managing this condition.

Several clinical studies have investigated plant sterols, including campesterol, for their cholesterol-lowering effects. Meta-analyses and systematic reviews have generally found that plant sterols can reduce LDL cholesterol by 5–15% when consumed at doses of 2 grams per day. However, most studies do not isolate campesterol but rather look at mixtures of plant sterols and stanols. While lowering LDL cholesterol is beneficial, direct evidence that campesterol supplementation alone significantly improves overall metabolic syndrome parameters (such as glucose metabolism, blood pressure, or waist circumference) is limited.

Thus, while there is scientific rationale and some supporting data for the use of campesterol-containing phytosterols in improving lipid profiles—a component of metabolic syndrome—the evidence that campesterol alone treats or reverses metabolic syndrome as a whole remains modest. Most guidelines support plant sterols as adjuncts to diet for cholesterol management, but not as primary treatments for metabolic syndrome.

More about campesterol
More about Metabolic Syndrome

Other ingredients used for Metabolic Syndrome

Other health conditions supported by campesterol

Products containing campesterol

Pure Encapsulations CholestePure
Pure Encapsulations CholestePure
Metagenics Meta-Sitosterol™ 2.0