Evidence supporting the use of: Cyanidin
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cyanidin is an anthocyanin, a type of flavonoid found in various fruits and vegetables, particularly in berries, red cabbage, and purple corn. Its potential use in supporting or treating metabolic syndrome (MetS) is primarily justified by emerging scientific evidence from preclinical and limited human studies. Animal studies and in vitro experiments have suggested that cyanidin and its glycoside derivatives may improve insulin sensitivity, modulate glucose metabolism, reduce inflammation, and protect against oxidative stress—all mechanisms relevant to MetS. For example, research in rodents has demonstrated that cyanidin can reduce blood glucose levels, improve lipid profiles, and decrease markers of inflammation after high-fat or high-sugar diets. These effects are thought to be mediated by the antioxidant properties of cyanidin and its ability to modulate signaling pathways involved in metabolism, such as AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptors (PPARs).

However, direct clinical evidence in humans is limited. A small number of pilot trials using cyanidin-rich extracts (often from berries) suggest potential benefits in improving some markers of MetS, such as blood pressure and lipid profiles, but these studies are often confounded by other bioactive compounds present in the extracts, small sample sizes, and short durations. No large-scale, high-quality clinical trials have definitively established cyanidin's efficacy for MetS. Thus, while there is a scientific rationale and promising preclinical data, human evidence remains preliminary, resulting in a moderate but not strong evidence rating.

More about cyanidin
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Products containing cyanidin

We currently have no products on Vitabase that contain this ingredient.