Evidence supporting the use of: Cyanidin
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cyanidin is an anthocyanin, a type of flavonoid found in various fruits and vegetables, particularly in berries, red cabbage, and purple corn. Its potential use in supporting or treating metabolic syndrome (MetS) is primarily justified by emerging scientific evidence from preclinical and limited human studies. Animal studies and in vitro experiments have suggested that cyanidin and its glycoside derivatives may improve insulin sensitivity, modulate glucose metabolism, reduce inflammation, and protect against oxidative stress—all mechanisms relevant to MetS. For example, research in rodents has demonstrated that cyanidin can reduce blood glucose levels, improve lipid profiles, and decrease markers of inflammation after high-fat or high-sugar diets. These effects are thought to be mediated by the antioxidant properties of cyanidin and its ability to modulate signaling pathways involved in metabolism, such as AMP-activated protein kinase (AMPK) and peroxisome proliferator-activated receptors (PPARs).

However, direct clinical evidence in humans is limited. A small number of pilot trials using cyanidin-rich extracts (often from berries) suggest potential benefits in improving some markers of MetS, such as blood pressure and lipid profiles, but these studies are often confounded by other bioactive compounds present in the extracts, small sample sizes, and short durations. No large-scale, high-quality clinical trials have definitively established cyanidin's efficacy for MetS. Thus, while there is a scientific rationale and promising preclinical data, human evidence remains preliminary, resulting in a moderate but not strong evidence rating.

More about Cyanidin
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algal oil
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alpha-linolenic acid (ALA)
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anthocyanins
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bacillus subtilis
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barley
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beta-sitosterol
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bitter melon
black garlic
blueberry
brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
matcha
medium chain triglycerides (MCT)
moringa
naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
trans-pterostilbene
Urolithin A
vanadium
vanadyl sulfate
vitamin C
vitamin D
wheat grass
whey protein
xylooligosaccharides
zinc
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algae
kidney beans
AMP-activated protein kinase (AMPK)
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anthocyanidins
Ampelopsin
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Algal protein
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alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Bifidobacterium adolescentis
Beta-hydroxybutyrate
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Bean
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Brazil nut
Charantin
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Cyanobacteria
Capsinoids
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chlorogenic acid
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Chitin-Glucan Complex
Calanus finmarchicus
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corosolic acid
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peanut
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Products containing Cyanidin

We currently have no products on Vitabase that contain this ingredient.