Evidence supporting the use of: Dragon fruit
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Dragon fruit (Hylocereus spp.), also known as pitaya, has gained attention for its potential benefits in supporting metabolic syndrome, a cluster of conditions that increase the risk of heart disease, stroke, and diabetes. The scientific evidence is modest but present. Several animal studies have demonstrated beneficial effects of dragon fruit on parameters such as blood glucose, insulin resistance, and lipid profiles. For example, a 2016 study in rats published in PLOS ONE found that dragon fruit supplementation improved fasting blood glucose and insulin sensitivity. A few small clinical studies in humans have also been conducted. A 2017 randomized controlled trial published in the Journal of Medicinal Food reported that consuming red dragon fruit led to modest reductions in fasting plasma glucose among prediabetic subjects. Another pilot study suggested mild improvements in LDL cholesterol and triglyceride levels.

The proposed mechanisms include the fruit’s high content of dietary fiber, antioxidants (such as betalains, vitamin C, and polyphenols), and prebiotic oligosaccharides, all of which may contribute to improved glycemic control and lipid metabolism. However, limitations exist: most human trials are small and short-term, with inconsistent results. There is not yet robust or large-scale evidence to firmly establish dragon fruit as an effective intervention for metabolic syndrome. Therefore, while scientific investigation is underway and some data are promising, the current evidence is rated at 2/5—suggesting early but insufficient validation. Further large, well-designed human trials are needed.

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Products containing dragon fruit

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