Evidence supporting the use of: Flaxseed
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flaxseed (Linum usitatissimum) has gained attention for its potential benefits in supporting and treating Metabolic Syndrome (MetS), a cluster of conditions that increase the risk for cardiovascular disease and type 2 diabetes. The scientific rationale for flaxseed’s use largely centers on its high content of alpha-linolenic acid (an omega-3 fatty acid), lignans (phytoestrogens with antioxidant properties), and soluble fiber. Multiple randomized controlled trials and meta-analyses have reported that flaxseed supplementation can lead to modest improvements in several MetS components, including reductions in total cholesterol, LDL cholesterol, blood pressure, and fasting blood glucose.

A 2016 meta-analysis in the journal Clinical Nutrition found that flaxseed supplementation significantly reduced systolic and diastolic blood pressure in adults. Another 2020 meta-analysis in Nutrients highlighted flaxseed’s beneficial effects on lipid profiles and glycemic control. Mechanistically, the soluble fiber in flaxseed slows glucose absorption and improves insulin sensitivity, while lignans and omega-3 fatty acids exert anti-inflammatory and cardiovascular protective effects.

However, the overall magnitude of effect is modest, and variability exists across studies regarding dosage, duration, and population. While dietary flaxseed is not a standalone therapy, current scientific evidence supports its adjunctive use as part of a dietary strategy to manage Metabolic Syndrome. No major safety concerns have been reported with reasonable dietary intake. Thus, flaxseed's use is rooted in scientific validation rather than just tradition.

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