Evidence supporting the use of: Glucoraphanin
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glucoraphanin is a naturally occurring compound found in cruciferous vegetables, especially broccoli. It is a precursor to sulforaphane, a bioactive isothiocyanate. In recent years, there has been growing scientific interest in glucoraphanin and sulforaphane for their potential benefits in metabolic health, particularly in conditions like Metabolic Syndrome (MetS). Several in vitro and animal studies suggest that sulforaphane can modulate key pathways involved in inflammation, oxidative stress, and insulin sensitivity—all relevant to MetS. Some small human studies have indicated that broccoli sprout extracts (rich in glucoraphanin/sulforaphane) can improve markers such as fasting blood glucose, lipid profiles, and oxidative stress in individuals with components of MetS or type 2 diabetes. However, the overall quality and quantity of clinical evidence remains modest. Most human trials are small, short-term, and sometimes use enriched extracts rather than purified glucoraphanin. There is no longstanding tradition of using glucoraphanin specifically for metabolic health; its use is based on recent scientific hypotheses and findings. Thus, while there is preliminary scientific validation, particularly from mechanistic and early clinical studies, more robust, large-scale clinical trials are needed to confirm efficacy and establish clinical recommendations.

More about Glucoraphanin
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5,7-Dimethoxyflavone
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algal oil
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alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
anchovies
ankaflavin
anthocyanidins
anthocyanins
antirrhinin
Antrodia camphorata
apigenin
arabinoxylan
Arjunolic acid
Aronia melanocarpa
Ascophyllum nodosum
asparagus
astragaloside
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avocado
bacillus subtilis
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berberine
beta-glucan
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black garlic
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blueberry
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campesterol
camu camu
capsiate
capsinoids
cardarine
carnosic acid
caterpillar mushroom
charantin
chia seed
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chlorogenic acid
chokeberry
chromium
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conjugated linoleic acid (CLA)
corosolic acid
crocetin
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cyanobacteria
cynaropicrin
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D-Pinitol
DHA (docosahexaenoic acid)
dihydrocapsiate
dihydrolipoic acid
diosgenin
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dragon fruit
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ergothioneine
evodiamine
fisetin
flavanols
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fructan
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fucosterol
fucoxanthin
galactooligosaccharides
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ginger
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glucomannan
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guanidinopropionic acid (GPA )
guar gum
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hydroxycitric acid
hydroxytyrosol
inulin
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isomaltulose
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Products containing Glucoraphanin

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