Evidence supporting the use of: Irvingia gabonensis
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Irvingia gabonensis, commonly known as African mango, has garnered interest for its potential effects on components of metabolic syndrome, including obesity, dyslipidemia, and insulin resistance. Several small clinical trials have investigated extracts of Irvingia gabonensis seeds (often branded as IGOB131) in overweight or obese individuals. Some of these studies report modest reductions in body weight, waist circumference, and improvements in blood lipid profiles and markers of glycemic control after supplementation for periods ranging from 4 to 12 weeks. For example, a 2009 randomized controlled trial (Oben et al., Lipids in Health and Disease) found that participants receiving Irvingia gabonensis extract lost more weight and improved their cholesterol and blood glucose levels compared to placebo. However, the overall quality of the evidence is low: most studies are small, short-term, and sometimes sponsored by supplement manufacturers. There is a lack of large, independent, long-term trials confirming efficacy and safety. Additionally, while some traditional uses of the plant exist (mainly as a food and for treating other ailments), its use specifically for metabolic syndrome is based on recent scientific exploration rather than longstanding traditional medicine. In summary, there is some preliminary scientific evidence suggesting Irvingia gabonensis may support aspects of metabolic syndrome, but this evidence is currently limited and not robust enough to warrant strong conclusions or widespread clinical use.
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15,16-Dihydrotanshinone I
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
7-hydroxymatairesinol (HMR)
7-Keto-DHEA
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Acai berry
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algal oil
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Alpha Glucans
Alpha methyl tetradecylthioacetic acid
Alpha phytosterol
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
alpha-lipoic acid
AMP-activated protein kinase (AMPK)
ampelopsin
anchovies
ankaflavin
anthocyanidins
anthocyanins
antirrhinin
Antrodia camphorata
apigenin
arabinoxylan
Arjunolic acid
Aronia melanocarpa
Ascophyllum nodosum
asparagus
astragaloside
Auricularia
avocado
bacillus subtilis
banaba
barley
bean
berberine
beta-glucan
beta-hydroxybutyrate
beta-sitosterol
betanin
Bifidobacterium adolescentis
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black garlic
Blakeslea trispora
blueberry
Brazil nut
Brussel sprouts
butyrate triglyceride
Calanus finmarchicus
California chia
campesterol
camu camu
capsiate
capsinoids
cardarine
carnosic acid
caterpillar mushroom
charantin
chia seed
Chitin-Glucan Complex
chlorogenic acid
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
corosolic acid
crocetin
Crypthecodinium
curcumin
cyanidin
cyanobacteria
cynaropicrin
Cystoseira canariensis
D-Pinitol
DHA (docosahexaenoic acid)
dihydrocapsiate
dihydrolipoic acid
diosgenin
docosahexaenoic Acid
DPA (docosapentaenoic acid)
dragon fruit
Dunaliella
Ecklonia
epigallocatechin gallate (EGCG)
ergothioneine
evodiamine
fisetin
flavanols
flaxseed
Foxtail millet
fructan
fructooligosaccharides (FOS)
fucosterol
fucoxanthin
galactooligosaccharides
garbanzo bean
ginger
Ginsenosides
Glucan peptides
glucomannan
Glucoraphanin
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guanidinopropionic acid (GPA )
guar gum
Guggulsterones
hydroxycitric acid
hydroxytyrosol
inulin
Irvingia gabonensis
Isoalantolactone
isomaltulose
Kamut
kidney beans
Konjac
krill oil
l-carnitine
Lactobacillus helveticus
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licorice root
lipstatin
lupin
maitake mushroom
mangiferin
maqui berry
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medium chain triglycerides (MCT)
Momordicosides
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Naringenin
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Neoeriocitrin
nicotinamide riboside
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oleanolic acid
oleic acid
Oleoylethanolamide
Oligosaccharides
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oolong tea
oyster mushroom
Palatinose
palmitoleic acid
peanut
Phaeophyceae
phlorizin
Phycocyanin
Phytoplankton
Pinitol
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Pleurotus eryngii
polychitosamine
Polydatin
polysaccharides
polyunsaturated fat
pu-er tea
punicalagins
punicalin
punicic acid
pyrroloquinoline quinone
quinoa
Rebaudioside
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reishi mushroom
resveratrol
rye
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Salidroside
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Schizochytrium
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Sesamin
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Sinensetin
spirulina
Sulforaphane
Syringic acid
Tagatose
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Tanshinone
Tetradecylthioacetic acid
Theabrownin
Theaflavin
Thylakoid
tocotrienols
Trans-pterostilbene
turmeric
Tyrosol
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Vanadium
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vitamin C
vitamin D
wheat grass
Whey protein
Xanthohumol
xylooligosaccharides
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Zinc
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Other health conditions supported by Irvingia gabonensis
Appetite (deficient)Cholesterol (high)
Diabetes
Hypertension
Metabolic Syndrome
Triglycerides (high)
Weight Loss