Evidence supporting the use of: MCT / Medium Chain Triglycerides
For the health condition: Metabolic Syndrome

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Medium Chain Triglycerides (MCTs) have been investigated for their potential benefits in metabolic syndrome, which is characterized by insulin resistance, obesity, dyslipidemia, and hypertension. The scientific basis for using MCTs lies in their unique absorption and metabolism. Unlike long-chain triglycerides, MCTs are absorbed directly into the portal circulation and rapidly oxidized for energy, which may enhance satiety and increase energy expenditure.

Several small clinical studies and animal experiments suggest that MCTs may promote modest weight loss, improve fat oxidation, and potentially reduce waist circumference, all of which are relevant to metabolic syndrome. Some evidence also suggests that MCTs may help improve insulin sensitivity and lipid profiles, though findings are inconsistent and generally weak.

A 2015 meta-analysis (St-Onge & Bosarge, 2015) found that replacing LCTs with MCTs resulted in small reductions in body weight and body fat in overweight individuals, but the impact on metabolic markers such as blood glucose and lipid profiles was limited. Most studies are short-term, use small sample sizes, and often lack rigorous controls.

Overall, while there is some scientific rationale and preliminary human evidence supporting the use of MCTs for aspects of metabolic syndrome (mainly weight management), robust, long-term clinical trials are lacking. Therefore, the evidence is limited and does not strongly support the use of MCTs as a primary treatment for metabolic syndrome.

More about MCT / Medium Chain Triglycerides
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Products containing MCT / Medium Chain Triglycerides

We currently have no products on Vitabase that contain this ingredient.