Evidence supporting the use of: Oleic acid
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Oleic acid, a monounsaturated fatty acid predominantly found in olive oil, is scientifically validated for its beneficial effects in the context of Metabolic Syndrome. Metabolic Syndrome is characterized by a cluster of conditions including insulin resistance, hypertension, dyslipidemia, and central obesity, all of which increase the risk of cardiovascular disease and type 2 diabetes. Epidemiological studies, particularly those examining the Mediterranean diet (which is rich in oleic acid), have consistently demonstrated a lower prevalence of Metabolic Syndrome and its components among populations with high dietary intake of monounsaturated fats.
Mechanistically, oleic acid has been shown to improve insulin sensitivity, reduce inflammation, and favorably modulate blood lipid profiles by decreasing LDL cholesterol and increasing HDL cholesterol. Several randomized controlled trials have demonstrated that substitution of saturated fats with monounsaturated fats, such as oleic acid, leads to improvements in markers of Metabolic Syndrome. However, while the overall evidence suggests benefit, it is often difficult to isolate the effects of oleic acid from other components of the Mediterranean diet, such as polyphenols and fiber.
In summary, the use of oleic acid to support or treat Metabolic Syndrome is backed by moderate scientific evidence, primarily through dietary patterns rich in this fatty acid. Direct supplementation with pure oleic acid is less studied, but increasing dietary sources of oleic acid (like olive oil) is widely recommended for metabolic health.
Other ingredients used for Metabolic Syndrome
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anchovies
anthocyanins
asparagus
bacillus subtilis
banaba
barley
berberine
Beta-Glucan
beta-sitosterol
bifidobacterium longum
bitter melon
black garlic
blueberry
brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
matcha
medium chain triglycerides (MCT)
moringa
naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
trans-pterostilbene
Urolithin A
vanadium
vanadyl sulfate
vitamin C
vitamin D
wheat grass
whey protein
xylooligosaccharides
zinc
β-nicotinamide mononucleotide (NMN)
algae
kidney beans
AMP-activated protein kinase (AMPK)
1-deoxynojirimycin
15,16-Dihydrotanshinone I
12-methylcarnosic acid
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
Alpha Glucans
Ankaflavin
Apigenin
Aronia melanocarpa
Antrodia camphorata
Auricularia
Antirrhinin
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Alpha phytosterol
Algal protein
Arabinoxylan
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Bifidobacterium adolescentis
Beta-hydroxybutyrate
Blakeslea trispora
Bean
Betanin
Brazil nut
Charantin
California chia
Cardarine
Cyanobacteria
Capsinoids
Cyanidin
chlorogenic acid
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
Cynaropicrin
Cystoseira canariensis
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Dunaliella
Dihydrocapsiate
Dragon Fruit
Dihydrolipoic Acid
D-Pinitol
Diosgenin
Ergothioneine
Ecklonia
peanut
Pistachio
Other health conditions supported by oleic acid
ArthritisCancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Diabetes
Fatty Liver Disease
Hypertension
Inflammation
Memory and Brain Function
Metabolic Syndrome
Triglycerides (high)