Evidence supporting the use of: Schizochytrium
For the health condition: Metabolic Syndrome
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Schizochytrium is a genus of marine microalgae notable for its high content of docosahexaenoic acid (DHA) and other omega-3 polyunsaturated fatty acids. Its use in supporting or treating Metabolic Syndrome is justified primarily by scientific research, though the level of evidence is moderate. Several preclinical and clinical studies have explored the impact of Schizochytrium-derived omega-3s on key components of Metabolic Syndrome, including dyslipidemia, inflammation, and insulin resistance.
Randomized controlled trials in humans have shown that Schizochytrium oil supplementation can reduce serum triglyceride levels and modestly improve lipid profiles—effects that are relevant for Metabolic Syndrome management. For example, a 2016 randomized trial (Fialkowski et al., J Clin Lipidol) found that supplementation with Schizochytrium-derived DHA led to significant reductions in triglycerides. Animal studies have further demonstrated improvements in insulin sensitivity and reductions in systemic inflammation after supplementation. However, effects on other parameters like blood glucose and waist circumference are less consistently reported.
Overall, the evidence for Schizochytrium’s benefit in Metabolic Syndrome is comparable to that for other omega-3 sources, though head-to-head studies are limited. Most clinical validation is tied to the omega-3 (DHA/EPA) content rather than unique properties of Schizochytrium itself. There is no traditional use of Schizochytrium in metabolic health, as its use is a modern development related to its omega-3 content. Thus, while promising, more large-scale and long-term trials are needed to fully establish efficacy.
Other ingredients used for Metabolic Syndrome
7-hydroxymatairesinol (HMR)7-Keto-DHEA
acai berry
akkermansia muciniphila
algal oil
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anchovies
anthocyanins
asparagus
bacillus subtilis
banaba
barley
berberine
Beta-Glucan
beta-sitosterol
bifidobacterium longum
bitter melon
black garlic
blueberry
brussel sprouts
butyrate triglyceride
campesterol
camu camu
canola oil
caterpillar mushroom
chia seed
chokeberry
chromium
cinnamon
conjugated linoleic acid (CLA)
turmeric
curcumin
DHA (docosahexaeonic acid)
DPA (docosapentaenoic acid)
epigallocatechin gallate (EGCG)
fisetin
flaxseed
fructooligosaccharides (FOS)
ginger
glucomannan
guar gum
hydroxycitric acid
inulin
krill oil
l-carnitine
lactobacillus helveticus
licorice root
mackerel
maitake mushroom
maqui berry
matcha
medium chain triglycerides (MCT)
moringa
naringin
nicotinamide riboside
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
quinoa
red yeast rice
reishi mushroom
resveratrol
rye
sardines
spirulina
tocotrienols
trans-pterostilbene
Urolithin A
vanadium
vanadyl sulfate
vitamin C
vitamin D
wheat grass
whey protein
xylooligosaccharides
zinc
β-nicotinamide mononucleotide (NMN)
algae
kidney beans
AMP-activated protein kinase (AMPK)
1-deoxynojirimycin
15,16-Dihydrotanshinone I
12-methylcarnosic acid
3-desoxy-7-KETO-DHEA
4-hydroxyisoleucine
5,7-Dimethoxyflavone
6-Paradol
Alpha Glucans
Ankaflavin
Apigenin
Aronia melanocarpa
Antrodia camphorata
Auricularia
Antirrhinin
Avocado
Ascophyllum nodosum
Acacetin
Alpha-Lipoic Acid
Astragaloside
anthocyanidins
Ampelopsin
Alpha phytosterol
Algal protein
Arabinoxylan
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Bifidobacterium adolescentis
Beta-hydroxybutyrate
Blakeslea trispora
Bean
Betanin
Brazil nut
Charantin
California chia
Cardarine
Cyanobacteria
Capsinoids
Cyanidin
chlorogenic acid
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
Cynaropicrin
Cystoseira canariensis
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Dunaliella
Dihydrocapsiate
Dragon Fruit
Dihydrolipoic Acid
D-Pinitol
Diosgenin
Ergothioneine
Ecklonia
peanut
Pistachio
Other health conditions supported by Schizochytrium
Alzheimer's DiseaseArthritis
Cardiovascular Disease
Cholesterol (high)
Fatty Liver Disease
Inflammation
Memory and Brain Function
Metabolic Syndrome
Rheumatoid Arthritis
Triglycerides (high)