Evidence supporting the use of: Black Hellebore
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Black Hellebore (Helleborus niger) has a long history of use in traditional European herbal medicine, including some historical references to its application for neurological complaints such as headaches and migraine-like symptoms. Ancient Greek and Roman physicians, such as Hippocrates and Dioscorides, mentioned hellebore as a remedy for various ailments, including what might now be classified as migraine or severe headaches. However, these references are broad, and the use of Black Hellebore was often associated with its purgative and emetic effects, which were thought to expel "bad humors" from the body. Modern scientific research on Black Hellebore for migraine is lacking; there are no well-conducted clinical studies or pharmacological investigations confirming its efficacy or safety for this indication. In fact, Black Hellebore contains toxic compounds (such as helleborin and helleborein) that can cause serious side effects, including nausea, vomiting, cardiac disturbances, and even death if used improperly. Due to its toxicity and lack of modern evidence, Black Hellebore is not recommended for migraine treatment today. Its historical use is acknowledged, but scientific validation is absent, and its inclusion in some traditional formulas is based primarily on pre-modern medical theories rather than evidence-based practice.

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Other ingredients used for Migraine

1,3,7-Trimethylpurine-2,6-dione
5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
Albizia
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
apple cider vinegar
ashwagandha
atractylodes
atractylone
Baikal Skullcap
balsam
banyan
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacteria
Black Hellebore
black seed
black tea
blackboard tree
Blepharis
brahmi
bupleurum falcatum
butterbur
cannabidiol
Carthamus
Chinese salvia root
Chinese silkvine
chrysanthemum
coenzyme Q10 (CoQ10)
cola nut
Corydalis
creatine
crocin
curcumin
danshen
DHA (docosahexaenoic acid)
docosahexaenoic Acid
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
feverfew
Ficus religiosa
Ficus simplicissima
fish
fish oil
flavanones
flavin mononucleotide
folic acid
frankincense
Gelsemium
ginger
ginkgo biloba
ginkgolides
Ginkgoside
goldthread
gooseberry
gotu kola
Hellebore
Indian frankincense
iridoids
ketone salts
kuding tea
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
lemon balm
Lesser speargrass
linalool
little ironweed
luteolin
magnesium
Meadowsweet
Melatonin
Mesua
Methylxanthine
Moringa
Nardostachys
Niacin (vitamin B3)
Night jessamine
omega-3 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Peppermint
Petasines
Phthalides
phytocannabinoids
pine bark
Polygonum
Puerarin
purple butterbur root
Pycnogenol
Rauvolfia
riboflavin (vitamin B2)
Rubiaceae
Rubus
rue
Salmon Oil
Sandalwood
Scabrous Gentian
Sensitive Plant
soursop
specialized pro-resolving mediators (SPMs)
Spikenard
Swertia
Szechuan lovage
turmeric
ubiquinol
Uncaria
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Withanolides
Xanthine
Xanthone
Xanthophyll
Yuzu
Zinc
Zingerone

Products containing Black Hellebore

We currently have no products on Vitabase that contain this ingredient.