Evidence supporting the use of: Cannabidiol
For the health condition: Migraine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Cannabidiol (CBD) has been explored as a potential treatment for migraine primarily based on its known anti-inflammatory, analgesic, and anti-emetic properties. However, the scientific evidence supporting its use for migraine is limited and largely preliminary. Most studies to date have focused on cannabis as a whole (containing both THC and CBD), rather than CBD alone. There is anecdotal evidence and a few small-scale studies or surveys suggesting that cannabinoids may reduce the frequency or severity of migraine attacks. For example, a 2017 study presented at the Congress of the European Academy of Neurology indicated that a combination of THC and CBD could reduce acute migraine pain by 40.4% in study participants, but the research was small and not placebo-controlled. Another 2020 review in Frontiers in Neurology noted that while cannabinoids may have a role in migraine management, rigorous clinical trials are lacking, and the mechanism is not fully understood.

To date, there are no large, high-quality randomized controlled trials specifically evaluating pure CBD for migraine prevention or treatment. Most migraine management guidelines do not recommend CBD due to insufficient evidence. Therefore, while there is some scientific rationale and preliminary investigation, the evidence is weak and insufficient for strong clinical endorsement at this time.

More about cannabidiol
More about Migraine

Other ingredients used for Migraine

1,3,7-Trimethylpurine-2,6-dione
5-Hydroxytryptophan (5-HTP)
5-methyltetrahydrofolate glucosamine
Albizia
Almond fruit
alpha-linolenic acid (ALA)
alpha-lipoic acid
apple cider vinegar
ashwagandha
atractylodes
atractylone
Baikal Skullcap
balsam
banyan
bergamot
beta caryophyllene
beta-hydroxybutyrate
betony
Bifidobacteria
Black Hellebore
black seed
black tea
blackboard tree
Blepharis
brahmi
bupleurum falcatum
butterbur
cannabidiol
Carthamus
Chinese salvia root
Chinese silkvine
chrysanthemum
coenzyme Q10 (CoQ10)
cola nut
Corydalis
creatine
crocin
curcumin
danshen
DHA (docosahexaenoic acid)
docosahexaenoic Acid
eicosapentaenoic acid
EPA (eicosapentaenoic acid)
feverfew
Ficus religiosa
Ficus simplicissima
fish
fish oil
flavanones
flavin mononucleotide
folic acid
frankincense
Gelsemium
ginger
ginkgo biloba
ginkgolides
Ginkgoside
goldthread
gooseberry
gotu kola
Hellebore
Indian frankincense
iridoids
ketone salts
kuding tea
kudzu
l-5-methyltetrahydrofolate glucosamine salt (5-MTHF)
lavender
lemon balm
Lesser speargrass
linalool
little ironweed
luteolin
magnesium
Meadowsweet
Melatonin
Mesua
Methylxanthine
Moringa
Nardostachys
Niacin (vitamin B3)
Night jessamine
omega-3 fatty acids
Osthole
paeoniflorin
Palmitoylethanolamide (PEA)
Peppermint
Petasines
Phthalides
phytocannabinoids
pine bark
Polygonum
Puerarin
purple butterbur root
Pycnogenol
Rauvolfia
riboflavin (vitamin B2)
Rubiaceae
Rubus
rue
Salmon Oil
Sandalwood
Scabrous Gentian
Sensitive Plant
soursop
specialized pro-resolving mediators (SPMs)
Spikenard
Swertia
Szechuan lovage
turmeric
ubiquinol
Uncaria
Valerian root
vitamin B6
vitamin D
vitamin D3
vitamin E
Withanolides
Xanthine
Xanthone
Xanthophyll
Yuzu
Zinc
Zingerone

Products containing cannabidiol

We currently have no products on Vitabase that contain this ingredient.