Evidence supporting the use of: Chinese Silkvine
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Chinese Silkvine (Periploca sepium) has been used in traditional Chinese medicine (TCM) primarily for its effects on pain, inflammation, and rheumatism. There is sparse documentation in historical TCM texts or pharmacopoeias specifically noting its use for migraine headaches. However, some general pain-relieving and anti-inflammatory properties have led to its occasional inclusion in multi-herb formulas targeting headaches or neuralgia. The mechanism is believed to be related to its ability to “dispel wind and dampness,” concepts in TCM often associated with pain syndromes including headaches.

From a scientific perspective, a limited number of studies have investigated the pharmacological actions of Chinese Silkvine, identifying some anti-inflammatory and analgesic effects in animal models. However, there is no direct clinical or preclinical evidence specifically linking Periploca sepium or its extracts to migraine prevention or treatment. The use of Chinese Silkvine for migraine relief is thus justified only by tradition, with minimal supporting evidence and no strong recommendation in modern TCM practice for this indication. The evidence rating reflects this lack of targeted research and the absence of robust clinical data.

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