Evidence supporting the use of: Danshen
For the health condition: Migraine

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Danshen (Salvia miltiorrhiza) is a traditional Chinese medicinal herb commonly used for its purported effects on blood circulation and cardiovascular health. Its use in the context of migraines is primarily rooted in traditional Chinese medicine (TCM) theory, where migraines are often attributed to "blood stasis" or poor circulation in the head. TCM practitioners have historically used Danshen, often in combination with other herbs, to "invigorate the blood" and alleviate headache symptoms, including migraines.

There is limited scientific investigation specifically addressing Danshen for migraine treatment. Some animal studies and in vitro research suggest that Danshen has anti-inflammatory, vasodilatory, and neuroprotective properties, which could, in theory, be relevant to migraine pathophysiology. However, robust human clinical trials evaluating Danshen alone or in combination for migraine prevention or treatment are lacking. The available evidence is largely anecdotal or based on traditional formulations, rather than modern, placebo-controlled studies.

In summary, the rationale for using Danshen in migraines is primarily traditional, supported by TCM texts and historical usage, with only preliminary and indirect scientific support for its mechanisms. Its effectiveness for migraine management has not been substantiated by high-quality clinical evidence.

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