Evidence supporting the use of: DHA
For the health condition: Migraine

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

DHA (docosahexaenoic acid) is an omega-3 fatty acid that has been investigated in relation to migraine, primarily due to its anti-inflammatory properties and potential neuroprotective effects. Several small studies and clinical trials have examined omega-3 supplementation (often as a combination of DHA and EPA) for migraine prevention. Some evidence suggests that omega-3s may modestly reduce the frequency, duration, or severity of migraine attacks, possibly by modulating neuroinflammation and improving vascular function. However, the results are inconsistent and not all studies have shown benefit. A 2018 systematic review and meta-analysis (Razeghi Jahromi et al., Cephalalgia) found limited and low-quality evidence to support omega-3 supplementation for migraine prophylaxis. Most clinical guidelines do not formally recommend DHA or omega-3s as a standard treatment for migraine due to insufficient robust evidence. There is no significant historical or traditional use of DHA for migraine; its use is based on a scientific rationale and preliminary clinical research. Overall, while there is some scientific investigation into DHA for migraine, the evidence remains limited, and further large, well-controlled trials are needed to establish efficacy and define dosing.

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Products containing DHA

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